Straathof J W A, Lüchtenborg M, Masclee A A M
Department of Gastroenterology-Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
Neurogastroenterol Motil. 2004 Apr;16(2):265-8. doi: 10.1111/j.1365-2982.2004.00500.x.
We have compared the sphinctometer with the water-perfused sleeve (gold standard) for measurement of lower oesophageal sphincter (LOS) characteristics by simultaneous recording. LOS pressure and transient LOS relaxations (TLOSR) measured by sleeve and sphinctometer in 11 healthy volunteers showed identical patterns. However, output of the sphinctometer was significantly (P < 0.01) lower than output of the sleeve. A total of 249 TLOSR were recorded. Of these, 176 TLOSR were identified by both sleeve and sphinctometer, 50 TLOSR were identified by sleeve alone and 23 TLOSR by sphinctometer alone. Due to the lower pressure output of the sphinctometer, 29 LOS relaxations did not reach criteria to qualify as TLOSRs. When TLOSR criteria were adjusted for sphinctometer pressure measurements, the number of TLOSRs identified by both sleeve and sphinctometer increased from 176 to 205. In conclusion, in healthy volunteers the sphinctometer registers TLOSR with results comparable with sleeve recording. However at low LOS pressures, the number of TLOSR is underscored by the sphinctometer.
我们通过同步记录，将括约肌测量仪与水灌注套囊（金标准）用于测量食管下括约肌（LOS）特征进行了比较。在11名健康志愿者中，用套囊和括约肌测量仪测量的LOS压力及短暂LOS松弛（TLOSR）呈现出相同的模式。然而，括约肌测量仪的输出显著低于套囊的输出（P < 0.01）。总共记录到249次TLOSR。其中，176次TLOSR可被套囊和括约肌测量仪同时识别，50次TLOSR仅由套囊识别，23次TLOSR仅由括约肌测量仪识别。由于括约肌测量仪的压力输出较低，29次LOS松弛未达到TLOSR的标准。当针对括约肌测量仪的压力测量调整TLOSR标准时，套囊和括约肌测量仪同时识别出的TLOSR数量从176次增加到205次。总之，在健康志愿者中，括约肌测量仪记录的TLOSR结果与套囊记录相当。然而，在低LOS压力下，括约肌测量仪记录的TLOSR数量会减少。
