McMahon Barry P, Drewes Asbjørn M, Gregersen Hans
Department of Medical Physics and Clinical Engineering, Adelaide and Meath Hospital, Tallaght, Dublin 24, Ireland.
World J Gastroenterol. 2006 May 14;12(18):2818-24. doi: 10.3748/wjg.v12.i18.2818.
Despite its role in disease there is still no definitive method to assess oesophago-gastric junction competence (OGJ). Traditionally the OGJ has been assessed using manometry with lower oesophageal sphincter pressure as the indicator. More recently this has been shown not to be a very reliable marker of sphincter function and competence against reflux. Disorders such as gastro-oesophageal reflux disease and to a lesser extend achalasia still effects a significant number of patients. This review looks at using a new technique known as impedance planimetry to profile the geometry and pressure in the OGJ during distension of a bag. The data gathered can be reconstructed into a dynamic representation of OGJ action. This has been shown to provide a useful representation of the OGJ and to show changes to the competence of the OGJ in terms of compliance and distensibility as a result of endoluminal therapy.
尽管食管胃交界部功能在疾病中起作用，但目前仍没有确定的方法来评估食管胃交界部的功能（OGJ）。传统上，OGJ是通过测压法进行评估的，以食管下括约肌压力作为指标。最近的研究表明，这并不是括约肌功能和抗反流能力的非常可靠的标志物。诸如胃食管反流病以及程度较轻的贲门失弛缓症等疾病仍然影响着大量患者。本综述探讨了使用一种称为阻抗平面测量法的新技术来描绘在气囊扩张过程中OGJ的几何形状和压力。收集到的数据可以重建为OGJ活动的动态表示。研究表明，这能有效地呈现OGJ，并显示腔内治疗后OGJ在顺应性和扩张性方面功能的变化。
