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[乳糜泻与自身免疫]

[Celiac disease and autoimmunity].

作者信息

Caiulo V A, Assanta N, Ceccarelli M

机构信息

Istituto di Clinica Pediatrica, Università di Pisa, Italia.

出版信息

Pediatr Med Chir. 1992 Mar-Apr;14(2):117-8.

PMID:1508749
Abstract

Immune mechanisms have been invoked to explain coeliac disease and associations between this and other immunologically mediated diseases have been described. A direct relationship proposed is that coeliac disease may be associated with a range of autoimmune disease through the formation of immune complexes in the small intestine. It's more probable a common origin in an inherited predisposition to hypersensitive immuno responses to extrinsic antigens or auto-antigens. The association between coeliac disease and particular histocompatibility antigens was recognised.

摘要

免疫机制已被用来解释乳糜泻,并且已经描述了它与其他免疫介导疾病之间的关联。一种提出的直接关系是,乳糜泻可能通过小肠中免疫复合物的形成与一系列自身免疫性疾病相关。更有可能的是,它起源于对外部抗原或自身抗原的超敏免疫反应的遗传易感性。人们认识到了乳糜泻与特定组织相容性抗原之间的关联。

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