Broyer Michel, Le Bihan Christine, Charbit Marina, Guest Genevieve, Tete Marie-Josephe, Gagnadoux Marie France, Niaudet Patrick
Department of Pediatric Nephrology, and Hôpital Necker Enfants Malades and University Paris V René Descartes, Paris, France.
Transplantation. 2004 Apr 15;77(7):1033-7. doi: 10.1097/01.tp.0000120947.75697.8b.
There are few data concerning the social outcome at adult age of children who received a kidney transplant. The aim of this study was to collect information on this outcome in a cohort of 366 children who underwent transplantation between 1973 and 1985.
Information was obtained through a simple questionnaire in 244 patients. The mean age of the patients was 31.7 years, and they had undergone grafting at a mean age of 11.9 years.
As of December 2000 or at last visit, 77% had a functioning graft. The mean height was 156.6 cm for male patients and 147.4 cm for female patients. The distribution of educational level was lower than national averages: 27.4% were at the lowest level versus 3% of the general population, 41.4% were at the middle level, 31.2% had reached the baccalaureate level, and 11% had followed a university cursus. Activity was similar to the general population: 73% had paid employment versus 72%, 6.5% were unemployed versus 10.5%, and 18.7% received a disablement pension. Among the 149 male patients, 39 (27%) had a marital life and 12 (8.3%) had children, whereas among the 95 female patients, 48 (50%) had a marital life and 26 (27%) had at least one child. Lodging was the parent's home in 46% and independent in 54%. Multivariate analysis showed a significant correlation between educational level, paid activity, marital life, and independent housing with final height.
The long-term social outcome of patients who underwent grafting in childhood more than 15 years previously is encouraging. The importance of reaching a normal height is stressed.
关于接受肾移植儿童成年后的社会结局的数据较少。本研究的目的是收集1973年至1985年间接受移植的366名儿童队列中这一结局的信息。
通过简单问卷获取了244名患者的信息。患者的平均年龄为31.7岁，他们接受移植时的平均年龄为11.9岁。
截至2000年12月或最后一次随访时，77%的患者移植肾仍在发挥功能。男性患者的平均身高为156.6厘米，女性患者为147.4厘米。教育水平分布低于全国平均水平：27.4%处于最低水平，而普通人群为3%；41.4%处于中等水平；31.2%达到学士学位水平；11%接受过大学教育。活动情况与普通人群相似：73%有带薪工作，普通人群为72%；6.5%失业，普通人群为10.5%；18.7%领取残疾抚恤金。在149名男性患者中，39名（27%）有婚姻生活，12名（8.3%）有子女；而在95名女性患者中，48名（50%）有婚姻生活，26名（27%）至少有一个孩子。46%的患者居住在父母家中，54%为独立居住。多变量分析显示教育水平、带薪活动、婚姻生活和独立住房与最终身高之间存在显著相关性。
15年多以前童年时期接受移植患者的长期社会结局令人鼓舞。强调了达到正常身高的重要性。
