Suppr超能文献

美国胃肠病学会静脉曲张出血管理指南的依从性变化:一项区域调查

Changing compliance to the American College of Gastroenterology guidelines for the management of variceal hemorrhage: a regional survey.

作者信息

Zaman Atif, Hapke Ronald J, Flora Kenneth, Rosen Hugo R, Benner Kent G

机构信息

Department of Medicine, Division of Gastroenterology and Hepatology, Oregon Health & Science University, Portland, Oregon 97201, USA.

出版信息

Am J Gastroenterol. 2004 Apr;99(4):645-9. doi: 10.1111/j.1572-0241.2004.04145.x.

Abstract

OBJECTIVES

In mid-1997 the American College of Gastroenterology (ACG) published guidelines for the management of varices. The aim of this study is to assess the change in regional practice patterns between early 1997 (preguidelines) and 2000 (postguidelines).

METHODS

Gastroenterologists in Oregon and Southwestern Washington state were sent a self-reporting questionnaire regarding the management of varices in March 1997 (prior to the publication of the guidelines) and again in August 2000.

RESULTS

Fifty-seven of 75 (76%) and 68 of 92 (74%) of the surveys were completed in 1997 and 2000, respectively. Fifty to 60% of the respondents saw between three and five cirrhotic patients per month. Significantly, more respondents followed the guidelines to screen and treat large varices to prevent initial variceal hemorrhage in 2000 than in 1997, 54% versus 18% (p < 0.005). Of the respondents who performed screening of EGDs, the majority treated large varices with beta-blocker therapy (93% in 1997 and 97% in 2000). All respondents used early endoscopy to treat variceal bleeding. Significantly, most of the respondents began pharmacologic therapy prior to endoscopy if active variceal hemorrhage was suspected (with most choosing octreotide) in 2000 than in 1997, 83% versus 56% (p < 0.005). The majority of the respondents pursued repeat endoscopic therapy after cessation of the initial variceal bleeding episode (96% in 1997 and 95% in 2000), and most performed surveillance EGD once the varices had been eradicated (72% in 1997 and 79% in 2000).

CONCLUSIONS

After the publication of the ACG guidelines, significantly more gastroenterologists screened for varices to prevent initial variceal hemorrhage and significantly more used pharmacologic therapy prior to endoscopic treatment for variceal hemorrhage.

摘要

目的

1997年年中,美国胃肠病学会(ACG)发布了静脉曲张管理指南。本研究的目的是评估1997年初(指南发布前)至2000年(指南发布后)区域实践模式的变化。

方法

1997年3月(指南发布前)和2000年8月,分别向俄勒冈州和华盛顿州西南部的胃肠病学家发送了一份关于静脉曲张管理的自填式问卷。

结果

1997年和2000年分别完成了75份调查中的57份(76%)和92份调查中的68份(74%)。50%至60%的受访者每月诊治3至5名肝硬化患者。值得注意的是,2000年遵循指南筛查和治疗大静脉曲张以预防初次静脉曲张出血的受访者比1997年显著增多,分别为54%和18%(p<0.005)。在进行内镜检查筛查的受访者中,大多数采用β受体阻滞剂治疗大静脉曲张(1997年为93%,2000年为97%)。所有受访者均采用早期内镜治疗静脉曲张出血。值得注意的是,2000年与1997年相比,如果怀疑有活动性静脉曲张出血,大多数受访者在进行内镜检查之前开始药物治疗(大多数选择奥曲肽),分别为83%和56%(p<0.005)。大多数受访者在初次静脉曲张出血发作停止后进行重复内镜治疗(1997年为96%,2000年为95%),并且大多数在静脉曲张根除后进行内镜监测(1997年为72%,2000年为79%)。

结论

ACG指南发布后,显著更多的胃肠病学家筛查静脉曲张以预防初次静脉曲张出血,并且显著更多的人在静脉曲张出血的内镜治疗之前使用药物治疗。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验