Li Melissa K, Folpe Andrew L
Department of Pathology, University of Florida, Gainesville, Florida, USA.
Adv Anat Pathol. 2004 Mar;11(2):101-5. doi: 10.1097/00125480-200403000-00004.
CDX2-88 is a recently developed monoclonal antibody to the intestinal epithelia-specific nuclear transcription factor CDX2. CDX2 immunohistochemistry has recently been shown to be useful in establishing gastrointestinal origin in metastatic tumors and will likely become a useful addition to the standard panel of immunostains for carcinomas of unknown primary sites. This article reviews the previous studies of this new antibody.
