Diotallevi P, Montella F, Di Sora F, Iacopini G, Simili C
Ospedale San Giovanni in Laterano, Roma.
Radiol Med. 1992 Jul-Aug;84(1-2):59-63.
This study was aimed at assessing the sensitivity of double-contrast esophagography in diagnosing Candida esophagitis. This condition accounts for 85% of all esophageal infections in the subjects suffering from AIDS. Thirty-nine HIV+ patients were evaluated: 19 of them had endoscopic diagnosis of Candida esophagitis. Our study confirmed the high sensitivity of esophagography (90%), as reported in the literature. Radiographic findings were edematous esophageal folds in the early stage and, subsequently, plaques and diffuse ulcerations. These patterns are suggestive of anatomical lesions: in the early stage, mucosal edema and erythema are observed, and later on pseudomembranes and ulcerations. None of our patients exhibited stenosis. All the subjects with Candida esophagitis had less than 250/mm3 of CD4 lymphocytes. In conclusion, double-contrast esophagography must be included in the periodic examinations performed on patients with AIDS, so as to allow an early diagnosis.
本研究旨在评估双重对比食管造影在诊断念珠菌性食管炎中的敏感性。在艾滋病患者中，这种疾病占所有食管感染的85%。对39例HIV阳性患者进行了评估：其中19例经内镜诊断为念珠菌性食管炎。我们的研究证实了食管造影的高敏感性（90%），正如文献中所报道的那样。影像学表现为早期食管皱襞水肿，随后出现斑块和弥漫性溃疡。这些表现提示存在解剖学病变：早期观察到黏膜水肿和红斑，后期出现假膜和溃疡。我们的患者均未出现狭窄。所有念珠菌性食管炎患者的CD4淋巴细胞计数均低于250/mm³。总之，双重对比食管造影必须纳入对艾滋病患者进行的定期检查中，以便能够早期诊断。
