Eckert Thomas, Eidelberg David
Dept. of Neurology II, University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany.
Clin Auton Res. 2004 Apr;14(2):84-91. doi: 10.1007/s10286-004-0167-1.
Parkinsonism is a symptom of a number of neurodegenerative disorders in the elderly. Even though clinical criteria for various parkinsonian disorders have been developed recently, the differential diagnosis of parkinsonian disorders based on clinical symptoms remains unsatisfactory, particularly in early disease stages. Early differential diagnosis on the other hand is important as prognosis and treatment options differ substantially. Multiple system atrophy (MSA) is one of the major differential diagnoses of idiopathic Parkinson's disease (PD). Radiotracer-based imaging methods such as positron emission tomography (PET) remain the established method for differential diagnosis of parkinsonian disorders. The following paper provides a review of different PET imaging methods for the differential diagnosis of PD and MSA patients.
帕金森综合征是老年人多种神经退行性疾病的一种症状。尽管最近已经制定了各种帕金森病性障碍的临床标准，但基于临床症状对帕金森病性障碍进行鉴别诊断仍不尽人意，尤其是在疾病早期阶段。另一方面，早期鉴别诊断很重要，因为预后和治疗方案差异很大。多系统萎缩（MSA）是特发性帕金森病（PD）的主要鉴别诊断之一。基于放射性示踪剂的成像方法，如正电子发射断层扫描（PET），仍然是帕金森病性障碍鉴别诊断的既定方法。以下论文综述了用于鉴别诊断帕金森病和多系统萎缩患者的不同PET成像方法。
