Ulukutlu L, Hitzig W, Maurer R
Department of Pediatrics, Istanbul University Cerrahpaşa Faculty of Medicine.
Turk J Pediatr. 1992 Jan-Mar;34(1):37-41.
A case of peripheral type T-cell lymphoma is presented to underline the difficulty in distinguishing the initial clinical findings of an inflammatory neoplastic disorder since the diagnosis could only be arrived at after several repeated lymph node biopsies. An 11 10/12-year-old boy admitted to the hospital with inguinal lymph node enlargement was diagnosed as having adenitis and periadenitis. The disease had progressed and the patient had remittent fever rising to 39 degrees C, and another biopsy was taken. Cervical lymphadenomegaly was present, A diagnosis of chronic lymphadenitis with lymphocyte loss and fibrosis was established. The diagnosis could only be made from biopsy material taken from the deep cervical (jugularis interna) and axillary lymph nodes one year later, which showed Ki-1 antigen positive large T-cell lymphoma. The disease showed continuous activity in spite of chemotherapy and the child survived only 17 months.
本文报告一例外周型T细胞淋巴瘤，旨在强调鉴别炎性肿瘤性疾病初始临床症状的困难，因为只有经过多次重复淋巴结活检才能确诊。一名11又10/12岁的男孩因腹股沟淋巴结肿大入院，最初被诊断为腺炎和腺周炎。病情进展，患者出现弛张热，体温高达39摄氏度，遂再次进行活检。此时发现有颈部淋巴结肿大，诊断为慢性淋巴细胞减少性纤维化性淋巴结炎。一年后，取自颈深部（颈内静脉旁）和腋窝淋巴结的活检材料显示为Ki-1抗原阳性大T细胞淋巴瘤，才最终确诊。尽管进行了化疗，病情仍持续进展，患儿仅存活了17个月。
