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两名HIV阳性女性的嗜酸性毛囊炎

Eosinophilic folliculitis in 2 HIV-positive women.

作者信息

Hayes Benjamin B, Hille Rachel C, Goldberg Lynne J

机构信息

Department of Medicine, Chattanooga Unit University of Tennessee College of Medicine, Chattanooga, USA.

出版信息

Arch Dermatol. 2004 Apr;140(4):463-5. doi: 10.1001/archderm.140.4.463.

DOI:10.1001/archderm.140.4.463
PMID:15096375
Abstract

BACKGROUND

Human immunodeficiency virus-associated eosinophilic folliculitis (HIV-EF) among homosexual men is a commonly reported dermatologic finding, while only 4 cases in HIV-positive women have been documented in the literature to date. This article describes 2 additional cases of HIV-EF in immunocompromised women and reviews the data on this condition.

OBSERVATIONS

The diagnoses were made on the basis of clinical appearance and microscopic analysis of skin biopsies. The women were not receiving highly active antiretroviral therapy (HAART) and their CD4 cell counts were below 100/ micro L.

CONCLUSIONS

As HIV prevalence continues to increase in the female population, more cases of HIV-EF will be seen among women. Because the etiology of HIV-EF remains elusive, no single treatment stands above the rest although several successful therapies have been demonstrated. However, HAART restores the proper T-cell milieu, which seems to improve the course of this disease.

摘要

背景

同性恋男性中的人类免疫缺陷病毒相关嗜酸性毛囊炎(HIV-EF)是一种常见的皮肤表现,而迄今为止文献中仅记载了4例HIV阳性女性病例。本文描述了另外2例免疫功能低下女性的HIV-EF病例,并回顾了关于这种疾病的数据。

观察结果

诊断基于临床表现和皮肤活检的显微镜分析。这些女性未接受高效抗逆转录病毒治疗(HAART),且她们的CD4细胞计数低于100/微升。

结论

随着HIV在女性人群中的患病率持续上升,女性中将会出现更多HIV-EF病例。由于HIV-EF的病因仍不清楚,尽管已证实有几种成功的治疗方法,但没有一种治疗方法优于其他方法。然而,HAART可恢复适当的T细胞环境,这似乎能改善该病的病程。

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