Roveri N, Ripamonti A, Garbisa S, Volpin D
Connect Tissue Res. 1978;5(4):249-53. doi: 10.3109/03008207809152279.
Small-angle X-ray diffraction patterns of bovine, human and porcine media aortic wall show meridional reflections corresponding to a periodicity which suggest a molecular packing typical of tendon collagen. However the meridional intensity distribution of stretched air dried aortic samples appears different from that of air-dried tendon, probably because of the presence of a large amount of type III collagen with the environment, which are specific for aortic tissue. The stretched wet aortic samples show a marked decrease in intensity, revealing an extensive disorder in the axially-projected structure of the fibrils. When a loading system simulating the effect of blood pressure is applied to a ring of aorta, no evidence of orientation of collagen is seen by X-ray diffraction, as would be expected if collagen fibrils had an isotropic distribution inside the aorta media. Scanning electroni microscopy supports the existence of a network of collagen fibrils surrounding elastic lamellae.
牛、人及猪主动脉壁中层的小角X射线衍射图谱显示出与周期性相对应的子午线反射，这表明其分子排列具有典型的肌腱胶原蛋白特征。然而，拉伸风干的主动脉样本的子午线强度分布似乎与风干肌腱的不同，这可能是因为主动脉组织特有的大量III型胶原蛋白与周围环境的存在。拉伸的湿主动脉样本强度显著降低，这表明原纤维的轴向投影结构存在广泛的无序性。当将模拟血压作用的加载系统应用于主动脉环时，通过X射线衍射未发现胶原蛋白取向的证据，正如如果胶原蛋白原纤维在主动脉中层呈各向同性分布时所预期的那样。扫描电子显微镜证实了围绕弹性膜存在胶原蛋白原纤维网络。
