Luna S P, Massone F, Castro G B, Fantoni D T, Hussni C A, Aguiar A J
Animal Health Trust, Newmarket, Suffolk.
Vet Rec. 1992 Jul 11;131(2):33-5. doi: 10.1136/vr.131.2.33.
A combination of 0.5 mg/kg of methotrimeprazine, 0.1 mg/kg of midazolam and 100 mg/kg of a 10 per cent guaiphenesin solution was investigated for the induction of recumbency in 15 horses; the addition of 1.6 mg/kg of ketamine was also evaluated in 15 horses and anaesthesia was maintained with halothane in oxygen. The horses became recumbent quickly and smoothly and they recovered quietly, with little ataxia. Tachycardia occurred after induction, but no other changes from pre-operative values were observed until halothane in oxygen had been given, when hypothermia, hypotension, bradypnoea, hyperoxaemia, respiratory acidosis and decreased respiratory minute volume developed. Horses given ketamine in addition to methotrimeprazine, midazolam and guaiphenesin were easier to intubate and recovered more quickly than horses receiving only methotrimeprazine, midazolam and guaiphenesin.
研究了0.5毫克/千克的甲氧异丁嗪、0.1毫克/千克的咪达唑仑和100毫克/千克的10%愈创甘油醚溶液联合使用对15匹马进行诱导卧倒的效果；还评估了在另外15匹马中添加1.6毫克/千克氯胺酮的情况，并使用氧气中的氟烷维持麻醉。马匹迅速且平稳地卧倒，恢复安静，几乎没有共济失调。诱导后出现心动过速，但在给予氧气中的氟烷之前，未观察到与术前值有其他变化，此时出现体温过低、低血压、呼吸过缓、高氧血症、呼吸性酸中毒和呼吸分钟量减少。除甲氧异丁嗪、咪达唑仑和愈创甘油醚外还给予氯胺酮的马匹比仅接受甲氧异丁嗪、咪达唑仑和愈创甘油醚的马匹更容易插管且恢复更快。
