Seyfarth H-J, Pankau H, Winkler J, Wirtz H
Abteilung Pneumologie, Medizinische Klinik I der Universität Leipzig, Johannisallee 32, 04103 Leipzig, Germany.
Pneumologie. 2004 Apr;58(4):217-21. doi: 10.1055/s-2004-818412.
The reduction of right ventricular function characterizes patients with severe pulmonary hypertension (PAH). Monitoring right ventricular function therefore is important. Echocardiography is the method of choice for this purpose. The so called Tei-Index seems to be an adequate diagnostic tool with prognostic relevance. We here compared Tei-Index with parameters of right heart catheterization in patients with PAH.
Tei-Index was calculated in 42 patients from the sum of isovolumetric contraction time and relaxation time divided by ejection time. A right heart catheter was performed the same day and pulmonary arterial mean pressure (PAPm) as well as pulmonary arterial resistance (PAR), central venous saturation (SVO (2)), central venous pressure (ZVD) stroke volume (SV) and right ventricular ejection fraction (RVEF) were recorded.
Correlation were observed between in each case Tei-Index and RVEF (r = - 0.72; p < 0.001), SV (r = - 0.52; p < 0.001), ZVD (r = 0.65; p < 0.001) and SVO (2) (r = - 0.58; p < 0.001). Tei-index did not correlate with PAPm and PAR.
Correlations of Tei-Index with parameters of right ventricular function derived from right heart catheterization support the usefulness of 2D-doppler echocardiography for monitoring right heart function in PAH patients.
右心室功能降低是重度肺动脉高压（PAH）患者的特征。因此，监测右心室功能很重要。超声心动图是用于此目的的首选方法。所谓的Tei指数似乎是一种具有预后相关性的合适诊断工具。我们在此比较了PAH患者中Tei指数与右心导管检查参数。
计算了42例患者的Tei指数，即等容收缩时间与舒张时间之和除以射血时间。同日进行了右心导管检查，并记录了肺动脉平均压（PAPm）、肺动脉阻力（PAR）、中心静脉血氧饱和度（SVO₂）、中心静脉压（ZVD）、每搏输出量（SV）和右心室射血分数（RVEF）。
在每种情况下，均观察到Tei指数与RVEF（r = -0.72；p < 0.001）、SV（r = -0.52；p < 0.001）、ZVD（r = 0.65；p < 0.001）和SVO₂（r = -0.58；p < 0.001）之间存在相关性。Tei指数与PAPm和PAR无相关性。
Tei指数与源自右心导管检查的右心室功能参数之间的相关性支持二维多普勒超声心动图在监测PAH患者右心功能方面的有用性。
