Scognamiglio Antonio, Matteelli Gabriella, Pistelli Francesco, Baldacci Sandra, Carrozzi Laura, Viegi Giovanni
Unità di Epidemiologia Ambientale Polmonare, Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Pisa.
Ann Ist Super Sanita. 2003;39(4):467-84.
Chronic obstructive pulmonary disease (COPD) is an important cause of morbidity and mortality, all over the world. COPD, which was the sixth leading cause of death worldwide in 1990, will become the third one in 2020. COPD is a complex disease, influenced by genetic, behavioral, and environmental factors. The most important factor for developing COPD is tobacco smoke. Also environmental conditions represents risk for developing COPD. Furthermore, diet and a low socioeconomic status are correlated to the disease. Genetic factors, familial history, and childhood lower respiratory tract infections play an important role in the etiology of COPD. Burden of COPD is very high for community. Furthermore, the disease often is under-diagnosed and treated only at advanced stages, whilst it is a substantial health problem even among young adults. This needs to be taken into account by health personnel and decision-makers.
慢性阻塞性肺疾病(COPD)是全球发病和死亡的重要原因。COPD在1990年是全球第六大死因,到2020年将成为第三大死因。COPD是一种复杂的疾病,受遗传、行为和环境因素影响。导致COPD的最重要因素是烟草烟雾。此外,环境状况也是患COPD的风险因素。此外,饮食和低社会经济地位与该疾病相关。遗传因素、家族病史和儿童期下呼吸道感染在COPD的病因中起重要作用。COPD给社区带来的负担非常高。此外,该疾病常常诊断不足,仅在晚期才得到治疗,而它甚至在年轻人中也是一个严重的健康问题。卫生人员和决策者需要考虑到这一点。