囊性皮脂腺癌：它是穆尔-托里综合征的一个恒定的病理特征性标志物吗？

Cystic sebaceous carcinoma: is it a constant pathognomic marker for Muir-Torre syndrome?

作者信息

Al-Shobaili Hani A, AlGhamdi Khalid M, Al-Ghamdi Walid A

机构信息

Dermatology Department, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia.

出版信息

J Drugs Dermatol. 2007 May;6(5):540-3.

PMID:17679191

Abstract

Sebaceous carcinoma (SC) is a rare and aggressive cutaneous neoplasm. It may arise in ocular or extraocular sites. Approximately 25% of all reported cases of SC are extraocular. Cystic presentation of sebaceous neoplasm is rare. So far, cystic sebaceous neoplasia (CSN) has been reported only in association with Muir-Torre syndrome (MTS). Furthermore, CSN has recently been characterized as a marker lesion of MTS. We report a case of CSN of the nose that was not associated with MTS. Mohs micrographic surgery was performed with no recurrence for 2 years. Patients with MTS need long-term follow-up to detect possible future presentation of MTS.

摘要

皮脂腺癌（SC）是一种罕见且侵袭性的皮肤肿瘤。它可发生于眼部或眼外部位。所有报告的皮脂腺癌病例中约25%为眼外病例。皮脂腺肿瘤的囊性表现罕见。到目前为止，囊性皮脂腺肿瘤（CSN）仅在与穆尔-托雷综合征（MTS）相关的情况下被报道。此外，CSN最近被认为是MTS的标志性病变。我们报告一例鼻部CSN，其与MTS无关。采用莫氏显微外科手术治疗，2年无复发。患有MTS的患者需要长期随访，以检测未来可能出现的MTS表现。