异常子宫出血与子宫内膜癌的预后
Abnormal uterine bleeding and prognosis of endometrial cancer.
作者信息
Kimura T, Kamiura S, Yamamoto T, Seino-Noda H, Ohira H, Saji F
机构信息
Department of Gynecology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari, Osaka, Japan.
出版信息
Int J Gynaecol Obstet. 2004 May;85(2):145-50. doi: 10.1016/j.ijgo.2003.12.001.
OBJECTIVES
The aim of this study was to analyze the relationship between the period of abnormal uterine bleeding (AUB) and the prognosis of endometrial cancer.
METHODS
We reviewed 304 endometrial cancer patients who were diagnosed and treated between 1985 and 1998 in our hospital, and whose history of AUB and clinical parameters were clearly available from their charts. Pathological data and overall survival were compared between groups having different periods of AUB.
RESULTS
Duration of AUB had no impact on the prognosis of endometrial cancer. Patients diagnosed with endometrial cancer without AUB showed a significantly better 5-year overall survival rate than the patients diagnosed after the onset of AUB. The distribution of clinical stages and histological grades did not differ depending on AUB status.
CONCLUSIONS
The prognosis of endometrial cancer was determined by the histopathological character of the tumor. However, the diagnosis and treatment of endometrial cancer with some suspicious signs other than AUB might improve the prognosis.
目的
本研究旨在分析异常子宫出血（AUB）的时长与子宫内膜癌预后之间的关系。
方法
我们回顾了1985年至1998年间在我院诊断并接受治疗的304例子宫内膜癌患者，其AUB病史和临床参数可从病历中清晰获取。比较了不同AUB时长组之间的病理数据和总生存率。
结果
AUB的持续时间对子宫内膜癌的预后没有影响。诊断为无AUB的子宫内膜癌患者的5年总生存率显著高于AUB发病后诊断的患者。临床分期和组织学分级的分布不因AUB状态而异。
结论
子宫内膜癌的预后由肿瘤的组织病理学特征决定。然而，对有AUB以外其他可疑症状的子宫内膜癌进行诊断和治疗可能会改善预后。
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