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一项随机对照试验中,滚球电凝子宫内膜切除术与子宫球囊热消融术的疗效及满意率比较

Efficacy and satisfaction rate comparing endometrial ablation by rollerball electrocoagulation to uterine balloon thermal ablation in a randomised controlled trial.

作者信息

Van Zon-Rabelink Ingrid A A, Vleugels Michel P H, Merkus Hans M W M, De Graaf Ruurd

机构信息

Department of Obstetrics and Gynecology, Medical Spectrum Twente, 7500 KA Enschede, The Netherlands.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2004 May 10;114(1):97-103. doi: 10.1016/j.ejogrb.2003.10.010.

DOI:10.1016/j.ejogrb.2003.10.010
PMID:15099879
Abstract

OBJECTIVE

To compare two methods of endometrial ablation, hysteroscopic rollerball electrocoagulation (RBE) and non-hysteroscopic uterine balloon thermal ablation (Thermachoice trade mark ), regarding efficacy for reducing dysfunctional uterine bleeding and patients satisfaction rate.

METHODS

A randomised controlled study was performed in a teaching hospital at the department of gynaecology. One hundred and thirty-seven premenopausal women with dysfunctional uterine bleeding proved by validated menstrual score list were included. Endometrial ablation by a hysteroscopic or non-hysteroscopic method was performed by one gynaecologist.

RESULTS

Reduction of menstrual blood loss was significantly more successful at 24 months for thermal ablation with uterine balloon. Success rate measured by menstrual score < 185 for rollerball and thermal balloon ablation are equivalent at 12 and 24 months post-operatively. Satisfaction of the patients for both methods at 24 months post-operatively is not significantly different (respective 75% for rollerball and 80% for uterine balloon).

CONCLUSIONS

Endometrial ablation by uterine balloon thermal ablation (Thermachoice trade mark ) is equally effective as hysteroscopic RBE of the endometrium.

摘要

目的

比较两种子宫内膜去除方法,即宫腔镜滚球电凝术(RBE)和非宫腔镜子宫球囊热消融术(Thermachoice商标)在减少功能失调性子宫出血方面的疗效及患者满意度。

方法

在一家教学医院的妇科进行了一项随机对照研究。纳入了137名经有效月经评分表证实为功能失调性子宫出血的绝经前妇女。由一名妇科医生采用宫腔镜或非宫腔镜方法进行子宫内膜去除术。

结果

子宫球囊热消融术在24个月时减少月经失血的效果显著更佳。术后12个月和24个月时,滚球电凝术和热球囊消融术以月经评分<185衡量的成功率相当。术后24个月时,两种方法的患者满意度无显著差异(滚球电凝术为75%,子宫球囊热消融术为80%)。

结论

子宫球囊热消融术(Thermachoice商标)进行子宫内膜去除与宫腔镜下子宫内膜滚球电凝术效果相当。

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