高海拔地区母亲贫血对婴儿血细胞比容和氧合的影响。

Effect of maternal anemia at high altitude on infant hematocrit and oxygenation.

作者信息

Ramirez-Cardich Maria E, Saito Mayuko, Gilman Robert H, Escate Luis E, Strouse John J, Kabrhel Christopher, Johnson Colleen, Galchen Rivka, Bautista Christian T

机构信息

Asociación Benéfica Proyectos en Informática, Salud, Medicina y Agricultura (A. B. PRISMA), Lima, Peru.

出版信息

Am J Trop Med Hyg. 2004 Apr;70(4):420-4.

PMID:15100457

Abstract

Hematocrit levels were determined in 36 mothers living at high altitudes (3,750 meters) and their infant cord bloods to determine the effect of maternal anemia on the infant. The arterial oxygen saturation (SaO(2)) and respiratory rate of the infants were also followed during the first four months of life. There was a negative correlation between maternal hematocrit and infant hematocrit (r(s) = - 0.57). Nineteen babies born to anemic women (hematocrit < 41%) had a significantly higher mean hematocrit (59.9%) than those born to non-anemic mothers (55.8%; P = 0.003). The SaO(2) levels and respiratory rates of infants were not different between infants born to non-anemic and anemic mothers. At high altitudes, infants from mothers with anemia have higher hematocrits than those born to non-anemic mothers.

摘要

对36位居住在高海拔地区（3750米）的母亲及其婴儿脐带血进行了血细胞比容水平测定，以确定母体贫血对婴儿的影响。在婴儿出生后的前四个月，还对其动脉血氧饱和度（SaO₂）和呼吸频率进行了跟踪监测。母体血细胞比容与婴儿血细胞比容之间存在负相关（r(s)= - 0.57）。贫血女性（血细胞比容<41%）所生的19名婴儿的平均血细胞比容（59.9%）显著高于非贫血母亲所生婴儿（55.8%；P = 0.003）。非贫血母亲和贫血母亲所生婴儿的SaO₂水平和呼吸频率没有差异。在高海拔地区，贫血母亲所生婴儿的血细胞比容高于非贫血母亲所生婴儿。