Vaezi Michael F
Center for Swallowing and Esophageal Disorders, Department of Gastroenterology and Hepatology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Clin Cornerstone. 2003;5(4):32-8; discussion 39-40. doi: 10.1016/s1098-3597(03)90097-4.
Gastroesophageal reflux disease (GERD) may manifest as laryngitis, asthma, cough, or noncardiac chest pain. Diagnosing these extraesophageal manifestations may be difficult for primary care physicians because most patients do not have heartburn or regurgitation. Diagnostic tests have low specificity, and a cause-and-effect association between GERD and extraesophageal symptoms is difficult to establish. Response to aggressive acid suppression is often the best indication of GERD etiology in a patient with extraesophageal symptoms.
胃食管反流病(GERD)可能表现为喉炎、哮喘、咳嗽或非心源性胸痛。对于初级保健医生而言,诊断这些食管外表现可能具有挑战性,因为大多数患者没有烧心或反流症状。诊断测试的特异性较低,且难以确立GERD与食管外症状之间的因果关系。对于有食管外症状的患者,积极的抑酸治疗反应通常是GERD病因的最佳指征。