Lion Niels, Reymond Frédéric, Girault Hubert H, Rossier Joël S
Laboratoire d'Electrochimie Physique et Analytique, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Curr Opin Biotechnol. 2004 Feb;15(1):31-7. doi: 10.1016/j.copbio.2004.01.001.
There has been a recent trend towards the miniaturization of analytical tools, but what are the advantages of microfluidic devices and when is their use appropriate? Recent advances in the field of micro-analytical systems can be classified according to instrument performance (which refers here to the desired property of the analytical tool of interest) and two important features specifically related to miniaturisation, namely reduction of the sample volume and the time-to-result. Here we discuss the contribution of these different parameters and aim to highlight the factors of choice in the development and use of microfluidic devices dedicated to protein analysis.
最近出现了分析工具小型化的趋势，但是微流控设备的优势是什么，何时适合使用它们呢？微分析系统领域的最新进展可以根据仪器性能（这里指感兴趣的分析工具的期望特性）以及与小型化特别相关的两个重要特征进行分类，即样品体积的减少和出结果的时间。在这里，我们讨论这些不同参数的作用，旨在突出在开发和使用用于蛋白质分析的微流控设备时的选择因素。
