Zamir G, Sakran W, Horowitz Y, Koren A, Miron D
Pediatric Department A', Ha'Emek Medical Center, Afula, Israel.
Arch Dis Child. 2004 May;89(5):466-8. doi: 10.1136/adc.2002.019182.
To assess the yield of routine renal ultrasound (RUS) in the management of young children hospitalised with first uncomplicated febrile urinary tract infection (UTI).
All children aged 0-5 years who had been hospitalised over a two year period with first uncomplicated febrile UTI in a medium size institutional regional medical centre were included. Children with known urinary abnormalities and/or who had been treated with antibacterial agents within seven days before admission were excluded. All included children underwent renal ultrasonography during hospitalisation and voiding cystouretrography (VCUG) within 2-6 months. The yield of RUS was measured by its ability to detect renal abnormalities, its sensitivity, specificity, and positive and negative predictive values for detecting vesicoureteral reflux (VUR), and by its impact on UTI management.
Of 255 children that were included in the study, 33 children had mild to moderate renal pelvis dilatation on RUS suggesting VUR, of whom only nine had VUR on VCUG. On the other hand, in 36 children with VUR on VCUG the RUS was normal. The sensitivity, specificity, positive predictive value, and negative predictive value of abnormal RUS for detecting VUR were 17.7%, 87.6%, 23.5%, and 83.2% respectively. In none of the patients with abnormal RUS was a change in the management at or following hospitalisation needed.
Results show that the yield of RUS to the management of children with first uncomplicated UTI is questionable.
评估常规肾脏超声检查(RUS)在首次发生单纯性发热性尿路感染(UTI)的住院幼儿治疗中的应用价值。
纳入一家中等规模的地区性医疗中心在两年内首次因单纯性发热性UTI住院的所有0至5岁儿童。排除已知泌尿系统异常和/或入院前7天内接受过抗菌药物治疗的儿童。所有纳入的儿童在住院期间接受肾脏超声检查,并在2至6个月内接受排尿性膀胱尿道造影(VCUG)。通过检测肾脏异常的能力、其敏感性、特异性以及检测膀胱输尿管反流(VUR)的阳性和阴性预测值,以及其对UTI治疗的影响来衡量RUS的应用价值。
在纳入研究的255名儿童中,33名儿童的RUS显示有轻度至中度肾盂扩张,提示存在VUR,但其中只有9名儿童在VCUG检查中发现有VUR。另一方面,在36名VCUG检查显示有VUR的儿童中,RUS检查结果正常。RUS异常对检测VUR的敏感性、特异性、阳性预测值和阴性预测值分别为17.7%、87.6%、23.5%和83.2%。在RUS异常的患者中,住院期间或出院后均无需改变治疗方案。
结果表明,RUS在首次发生单纯性UTI儿童的治疗中的应用价值值得怀疑。