Department of Pediatrics, School of Medicine, Adıyaman University, Adiyaman, 02000, Turkey.
Indian J Pediatr. 2023 Jul;90(7):671-676. doi: 10.1007/s12098-022-04213-0. Epub 2022 Jun 30.
To determine the frequency of urinary system anomaly in children aged 0-18 y suffering from first urinary tract infection (UTI) and to establish which age group requires urinary ultrasonography (USG) screening.
Age and gender, urine culture, urinary USG, and urological imaging results among 247 children in the 0-18 y age group with a first diagnosis of UTI were investigated retrospectively.
Anomaly was detected at USG in 68 (27.5%) of the 247 patients suffering from first UTI. The most common anomaly was hydronephrosis. Non-E. coli micro-organisms were the pathogenic agents in 61.8% of patients with anomalies detected at USG. Being in the 0-5 y age group (OR: 0.524, 95% CI 0.284-0.970, p = 0.040) and presence of atypical UTI (OR: 4.746, 95% CI: 1.675-13.450, p = 0.003) emerged as independent predictive markers of severe urinary system pathologies on multiple regression analysis.
Based on the data in the present study, routine USG screening is recommended for children suffering from first UTI under the age of 5 y and for the children suffering from atypical UTI at all ages.
确定 0-18 岁首次患尿路感染(UTI)的儿童泌尿系统异常的频率,并确定哪个年龄段需要进行尿超声检查(USG)筛查。
回顾性研究了 247 例年龄在 0-18 岁的首次诊断为 UTI 的儿童的年龄、性别、尿液培养、尿 USG 和泌尿科影像学结果。
在 247 例首次 UTI 患者中,有 68 例(27.5%)在 USG 检查中发现异常。最常见的异常是肾积水。在 USG 检查中发现异常的患者中,有 61.8%的病原体是非大肠杆菌微生物。0-5 岁年龄组(OR:0.524,95%CI 0.284-0.970,p=0.040)和非典型 UTI(OR:4.746,95%CI:1.675-13.450,p=0.003)是多因素回归分析中严重泌尿系统疾病的独立预测指标。
根据本研究的数据,建议对 5 岁以下首次患 UTI 的儿童和所有年龄段患非典型 UTI 的儿童进行常规 USG 筛查。