Oshitari Kazuhiro, Hida Tetsuo, Takahashi Megumi, Okada Annabelle A, Shiobara Tetsuo
Department of Ophthalmology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka 181-8611, Japan.
Nippon Ganka Gakkai Zasshi. 2004 Mar;108(3):162-5.
A case of Sweet syndrome mimicking orbital cellulitis is reported.
A 17-year-old girl presented with painful eyelid swelling, limited ocular movement in the right eye, and an increased white cell count. The patient was initially diagnosed as having infectious orbital cellulitis, but her symptoms did not improve with administration of intravenous carbanpenem and cefzon. Systemic examination revealed erythema of the extremities, and blood tests showed elevated C-reactive protein. These findings are consistent with a diagnosis of Sweet syndrome, and the patient was treated with 30 mg of oral prednisone. The eyelid swelling and erythema of the extremities decreased one day after the initiation of corticosteroid therapy. Skin biopsy showed infiltration of neutrophils and histiocytes in the dermis, confirming the diagnosis of Sweet syndrome.
Sweet syndrome with eyelid and orbital involvement may mimic infectious orbital cellulitis.
报告一例疑似眼眶蜂窝织炎的Sweet综合征病例。
一名17岁女孩出现眼睑疼痛性肿胀、右眼眼球运动受限及白细胞计数升高。患者最初被诊断为感染性眼眶蜂窝织炎,但静脉注射碳青霉烯类药物和头孢唑肟后症状未改善。全身检查发现四肢红斑,血液检查显示C反应蛋白升高。这些发现符合Sweet综合征的诊断,患者接受了30毫克口服泼尼松治疗。糖皮质激素治疗开始一天后,眼睑肿胀和四肢红斑减轻。皮肤活检显示真皮层有中性粒细胞和组织细胞浸润,证实了Sweet综合征的诊断。
累及眼睑和眼眶的Sweet综合征可能酷似感染性眼眶蜂窝织炎。