Taravati Parisa
Department of Ophthalmology, University of Washington Seattle, Washington USA.
Neuroophthalmology. 2015 Jan 22;39(1):42-45. doi: 10.3109/01658107.2014.961090. eCollection 2015 Feb.
Neuro-Sweet disease is a rare condition causing encephalitis or meningitis in addition to the erythematous skin plaques of Sweet syndrome. Neuro-Sweet disease has been associated with several ocular manifestations, including ocular movement disorders, episcleritis, conjunctivitis, uveitis, and optic disc oedema. The author reports a patient with orbital inflammation, cranial neuropathies, and a skin rash in the setting of myelodysplastic syndrome. Biopsy of her skin lesion confirmed the diagnosis of neuro-Sweet disease. To the author's knowledge, this is the first reported case of neuro-Sweet disease causing orbital inflammation. Her ocular inflammation resolved with the use of systemic corticosteroid treatment.
神经-斯威特病是一种罕见病症，除了斯威特综合征的红斑性皮肤斑块外，还会引发脑炎或脑膜炎。神经-斯威特病与多种眼部表现有关，包括眼球运动障碍、巩膜炎、结膜炎、葡萄膜炎和视盘水肿。作者报告了一名患有骨髓增生异常综合征的患者，该患者出现眼眶炎症、颅神经病变和皮疹。对其皮肤病变进行活检确诊为神经-斯威特病。据作者所知，这是首例报道的由神经-斯威特病引起眼眶炎症的病例。通过全身使用皮质类固醇治疗，她的眼部炎症得到缓解。
