[阴沟肠杆菌临床分离株中质粒与噬菌体宿主范围之间关系的评估]
[Evaluation of relations between plasmids and phage host range among clinical isolates of Enterobacter cloacae].
作者信息
Nieradko Józef, Kurlenda Juliana
机构信息
Katedra Mikrobiologii Uniwersytetu Gdańskiego w Gdańsku.
出版信息
Med Dosw Mikrobiol. 2003;55(4):343-9.
PMID:15103993
Abstract
The aim of this study was evaluation the plasmid influence on phage host range of clinical strains of Enterobacter cloacae. We found that strains included in restrictive pattern A, displayed reduced host range. Such reduced sensitivity make these strains excellent candidates for search restrictive-modification systems. High discriminative efficacy of isolated phages (specific for strains Enterobacter cloacae) make them useful tool for phage typing in epidemiological investigations.
摘要
本研究的目的是评估质粒对阴沟肠杆菌临床菌株噬菌体宿主范围的影响。我们发现，纳入限制模式A的菌株显示出宿主范围缩小。这种敏感性降低使这些菌株成为寻找限制修饰系统的极佳候选对象。分离出的噬菌体（对阴沟肠杆菌菌株具有特异性）的高鉴别效力使其成为流行病学调查中噬菌体分型的有用工具。
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