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尿症状问卷与尿动力学诊断之间的关系:两种问卷施测方法的分析。

The relationship between urinary symptom questionnaires and urodynamic diagnoses: an analysis of two methods of questionnaire administration.

作者信息

Khan Mohid S, Chaliha Charlotte, Leskova Lucia, Khullar Vikram

机构信息

Department of Obstetrics and Gynaecology, Mint Wing, St Mary's Hospital, Imperial College, London, UK.

出版信息

BJOG. 2004 May;111(5):468-74. doi: 10.1111/j.1471-0528.2004.00126.x.

Abstract

OBJECTIVE

To assess whether method of administration of a standard urinary symptom questionnaire alters the relationship of symptoms with urodynamic diagnoses.

DESIGN

Randomised crossover study.

SETTING

Tertiary Urogynaecology Unit, London, UK.

PARTICIPANTS

One hundred and fourteen women attending a tertiary urogynaecology clinic.

METHODS

Women were randomised to either an initial interview-assisted questionnaire in the clinic with a follow up postal questionnaire or an initial pre-outpatient questionnaire followed by an interview-assisted questionnaire at the clinic visit. Video cystourethrography or saline cystometry was performed at the clinic visit.

MAIN OUTCOME MEASURES

Question responses were compared with urodynamic diagnoses.

RESULTS

With an interview method, only severity of incontinence was significantly associated with detrusor overactivity (U= 593.5, P= 0.012). With self-completion, severity of nocturia (U= 477, P < 0.05), urgency (U= 395, P= 0.003), urge urinary incontinence (U= 392, P= 0.003), leakage without warning (U= 443, P= 0.035) and incomplete voiding (U= 413, P= 0.01) were significantly associated with detrusor activity. On interview the symptom of stress urinary incontinence (U= 523, P= 0.002) and use of pads (U= 564.5, P= 0.011) were significantly associated with a diagnosis of urodynamic stress incontinence. Severity of stress urinary incontinence (U= 276, P < 0.001), frequency of leakage (U= 348.5, P= 0.004), use of protection (U= 432.5, P < 0.018), nocturnal incontinence (U= 393.5, P= 0.002) and quantity of leakage (U= 441.5, P < 0.05) on self-completion were strongly associated with diagnosed urodynamic stress incontinence. There was no association between the symptoms of urgency or urge incontinence and the urodynamic stress incontinence.

CONCLUSIONS

Postal questionnaire responses have a better relationship with urodynamics, both for urodynamic stress incontinence and detrusor over activity, than interview-assisted questionnaire responses. However, no symptom has a high enough specificity and sensitivity to replace urodynamic testing.

摘要

目的

评估标准泌尿症状问卷的施用方法是否会改变症状与尿动力学诊断之间的关系。

设计

随机交叉研究。

地点

英国伦敦的三级泌尿妇科单位。

参与者

114名前往三级泌尿妇科诊所就诊的女性。

方法

女性被随机分为两组,一组是在诊所进行初始访谈辅助问卷,随后进行邮寄问卷随访;另一组是在门诊前进行初始问卷,然后在诊所就诊时进行访谈辅助问卷。在诊所就诊时进行视频膀胱尿道造影或盐水膀胱测压。

主要观察指标

将问卷回答与尿动力学诊断进行比较。

结果

采用访谈法时,只有尿失禁严重程度与逼尿肌过度活动显著相关(U = 593.5,P = 0.012)。采用自我填写法时,夜尿严重程度(U = 477,P < 0.05)、尿急(U = 395,P = 0.003)、急迫性尿失禁(U = 392,P = 0.003)、无预警漏尿(U = 443,P = 0.035)和排尿不完全(U = 413,P = 0.01)与逼尿肌活动显著相关。访谈时,压力性尿失禁症状(U = 523,P = 0.002)和护垫使用情况(U = 564.5,P = 0.011)与尿动力学压力性尿失禁诊断显著相关。自我填写时,压力性尿失禁严重程度(U = 276,P < 0.001)、漏尿频率(U = 348.5,P = 0.004)、防护用品使用情况(U = 432.5,P < 0.018)、夜间尿失禁(U = 393.5,P = 0.002)和漏尿量(U = 441.5,P < 0.05)与诊断的尿动力学压力性尿失禁密切相关。尿急或急迫性尿失禁症状与尿动力学压力性尿失禁之间无关联。

结论

对于尿动力学压力性尿失禁和逼尿肌过度活动,邮寄问卷的回答与尿动力学的关系比访谈辅助问卷的回答更好。然而,没有一种症状具有足够高的特异性和敏感性来替代尿动力学检测。

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