Digesu G Alessandro, Salvatore Stefano, Fernando Ruwan, Khullar Vik
Department of Urogynaecology, St. Mary's Hospital, London, United Kingdom.
Neurourol Urodyn. 2008;27(5):372-5. doi: 10.1002/nau.20530.
To define the urodynamic diagnoses of women with mixed urinary incontinence (MUI) symptoms.
Women with MUI symptoms were studied. They were divided into stress predominant MUI; urge predominant MUI; or equal severity of stress and urge MUI on the basis of the most severe symptom scored on the King's Health Questionnaire. The frequency of different urodynamic diagnoses for the all women with MUI and in each of the above groups was calculated.
Overall 3,338 women were studied. Of these 49% (1,626/3,338) reported MUI symptoms and were included. In this group 29% (464/1,626) had stress predominant MUI, 15% (248/1,626) had urge predominant MUI and 56% (912/1,626) had equal severity of urge and stress MUI. On urodynamics 42% (665/1,626) had pure urodynamic stress incontinence, 25% (414/1,626) had pure detrusor overactivity, 18% (299/1,626) had both detrusor overactivity and urodynamic stress incontinence and 15% (248/1,626) had normal urodynamic studies. In those with stress predominant MUI, 82% had urodynamic stress incontinence; in those with urge predominant MUI, 64% had detrusor overactivity. The urodynamic diagnoses were significantly different for the different balance of symptoms (P < 0.05, Chi-Square test). In women with equal severity of urge and stress incontinence, 46% had detrusor overactivity while 54% had urodynamic stress incontinence.
The relative severity of MUI symptoms from a symptom questionnaire significantly distinguishes between different urodynamic diagnoses. Women with urge predominant MUI are more likely to have detrusor overactivity while those with stress predominant MUI are more likely to have urodynamic stress incontinence.
明确有混合性尿失禁(MUI)症状女性的尿动力学诊断。
对有MUI症状的女性进行研究。根据国王健康问卷中得分最严重的症状,将她们分为以压力性为主的MUI;以急迫性为主的MUI;或压力性和急迫性严重程度相同的MUI。计算所有有MUI症状女性以及上述每组中不同尿动力学诊断的频率。
共研究了3338名女性。其中49%(1626/3338)报告有MUI症状并被纳入研究。在该组中,29%(464/1626)为以压力性为主的MUI,15%(248/1626)为以急迫性为主的MUI,56%(912/1626)为压力性和急迫性严重程度相同的MUI。尿动力学检查显示,42%(665/1626)为单纯性尿动力学压力性尿失禁,25%(414/1626)为单纯逼尿肌过度活动,18%(299/1626)为逼尿肌过度活动和尿动力学压力性尿失禁并存,15%(248/1626)尿动力学检查正常。在以压力性为主的MUI患者中,82%有尿动力学压力性尿失禁;在以急迫性为主的MUI患者中,64%有逼尿肌过度活动。不同症状平衡情况下的尿动力学诊断有显著差异(P<0.05,卡方检验)。在压力性和急迫性尿失禁严重程度相同的女性中,46%有逼尿肌过度活动,而54%有尿动力学压力性尿失禁。
症状问卷中MUI症状的相对严重程度能显著区分不同的尿动力学诊断。以急迫性为主的MUI女性更可能有逼尿肌过度活动,而以压力性为主的MUI女性更可能有尿动力学压力性尿失禁。