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A revival of bispecific antibodies.

作者信息

Kufer Peter, Lutterbüse Ralf, Baeuerle Patrick A

机构信息

Micromet AG, Staffelseestrasse 2, 81477 Munich, Germany.

出版信息

Trends Biotechnol. 2004 May;22(5):238-44. doi: 10.1016/j.tibtech.2004.03.006.

DOI:10.1016/j.tibtech.2004.03.006

PMID:15109810

Abstract

摘要

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A revival of bispecific antibodies.

作者信息

Kufer Peter, Lutterbüse Ralf, Baeuerle Patrick A

机构信息

Micromet AG, Staffelseestrasse 2, 81477 Munich, Germany.

出版信息

Trends Biotechnol. 2004 May;22(5):238-44. doi: 10.1016/j.tibtech.2004.03.006.

DOI:10.1016/j.tibtech.2004.03.006

PMID:15109810

Abstract

摘要

相似文献

A revival of bispecific antibodies.

Trends Biotechnol. 2004 May;22(5):238-44. doi: 10.1016/j.tibtech.2004.03.006.

Expression and purification of monospecific and bispecific recombinant antibody fragments derived from antibodies that block the CD80/CD86-CD28 costimulatory pathway.

Protein Expr Purif. 2001 Jun;22(1):11-24. doi: 10.1006/prep.2001.1417.

Recombinant bispecific antibodies for cellular cancer immunotherapy.

Curr Opin Mol Ther. 2007 Aug;9(4):319-26.

Therapeutic assessment of SEED: a new engineered antibody platform designed to generate mono- and bispecific antibodies.

Protein Eng Des Sel. 2011 May;24(5):447-54. doi: 10.1093/protein/gzq123.

[Bispecific antibodies: what future?].

Med Sci (Paris). 2009 Dec;25(12):1155-8. doi: 10.1051/medsci/200925121155.

Immunology. Two-in-one designer antibodies.

Science. 2009 Mar 20;323(5921):1567-8. doi: 10.1126/science.1172253.

Smarter drugs: a focus on pan-specific monoclonal antibodies.

BioDrugs. 2011 Dec 1;25(6):357-64. doi: 10.2165/11594690-000000000-00000.

Mitogenic properties of a bispecific single-chain Fv-Ig fusion generated from CD2-specific mAb to distinct epitopes.

Int Immunol. 1998 Dec;10(12):1863-72. doi: 10.1093/intimm/10.12.1863.

Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site.

Science. 2009 Mar 20;323(5921):1610-4. doi: 10.1126/science.1165480.

Construction and characterization of a bispecific anti-CD20 antibody with potent antitumor activity against B-cell lymphoma.

Cancer Res. 2010 Aug 1;70(15):6293-302. doi: 10.1158/0008-5472.CAN-10-0009. Epub 2010 Jul 14.

引用本文的文献

Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors.

PLoS Comput Biol. 2024 Jun 7;20(6):e1012157. doi: 10.1371/journal.pcbi.1012157. eCollection 2024 Jun.

A pivotal decade for bispecific antibodies?

MAbs. 2024 Jan-Dec;16(1):2321635. doi: 10.1080/19420862.2024.2321635. Epub 2024 Mar 11.

Candidate Biomarkers for Targeting in Type 1 Diabetes; A Bioinformatic Analysis of Pancreatic Cell Surface Antigens.

Cell J. 2024 Jan 31;26(1):51-61. doi: 10.22074/cellj.2023.1996297.1262.

Cross-linking disulfide bonds govern solution structures of diabodies.

Proteins. 2023 Sep;91(9):1316-1328. doi: 10.1002/prot.26509. Epub 2023 Jun 28.

Understanding the structure-property relationship of bispecific monoclonal antibodies with Fc site-specific substitutions.

MAbs. 2023 Jan-Dec;15(1):2228006. doi: 10.1080/19420862.2023.2228006.

The renaissance of chemically generated bispecific antibodies.

Nat Rev Chem. 2021 Feb;5(2):78-92. doi: 10.1038/s41570-020-00241-6. Epub 2021 Jan 19.

Generation of bispecific antibodies by structure-guided redesign of IgG constant regions.

Front Immunol. 2023 Jan 10;13:1063002. doi: 10.3389/fimmu.2022.1063002. eCollection 2022.

The making of multivalent gamma delta TCR anti-CD3 bispecific T cell engagers.

Front Immunol. 2023 Jan 5;13:1052090. doi: 10.3389/fimmu.2022.1052090. eCollection 2022.

Preparation of an Immunoaffinity Column Based on Bispecific Monoclonal Antibody for Aflatoxin B and Ochratoxin A Detection Combined with ic-ELISA.

Foods. 2022 Jan 25;11(3):335. doi: 10.3390/foods11030335.

Bispecific Aptamer Sensor toward T-Cell Leukemia Detection in the Tumor Microenvironment.

ACS Omega. 2021 Nov 19;6(48):32563-32570. doi: 10.1021/acsomega.1c04125. eCollection 2021 Dec 7.