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经瞳孔温热疗法治疗局限性脉络膜血管瘤

Transpupillary thermotherapy in the management of circumscribed choroidal hemangioma.

作者信息

Gündüz Kaan

机构信息

Ocular Oncology Service, Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.

出版信息

Surv Ophthalmol. 2004 May-Jun;49(3):316-27. doi: 10.1016/j.survophthal.2004.02.009.

Abstract

Laser photocoagulation and various radiation therapy methods have been used in the treatment of circumscribed choroidal hemangioma that produce visual loss. Recently, transpupillary thermotherapy has been employed in the management of choroidal hemangioma. Thirty-six cases of choroidal hemangioma treated with transpupillary thermotherapy are reviewed. Twenty-eight cases were reported in the literature and 10 cases were managed by the author. Transpupillary thermotherapy has been used as a primary treatment (36 cases) or secondary treatment (2 cases) for choroidal hemangioma. The goal of transpupillary thermotherapy is to achieve resolution of exudative detachment of the fovea and improvement of vision. In all eyes the foveal detachment subsided. In 26 eyes having pretreatment visual acuity >or=0.05 (20/400), the visual acuity increased in 20 (77%) eyes and remained unchanged in 6 (23%) eyes. After transpupillary thermotherapy, 16 (42%) cases showed complete regression, 20 (53%) demonstrated partial regression, and in 2 (5%) there was no change in tumor thickness at follow-ups ranging from 2 to 44 months. Complications of transpupillary thermotherapy of choroidal hemangioma included cystoid macular edema (3 eyes), preretinal fibrosis (2 eyes), focal iris atrophy (3 eyes), and retinal vascular occlusion (1 eye). Although the follow-up in many studies is limited, transpupillary thermotherapy has not been associated with any significant complications.

摘要

激光光凝和各种放射治疗方法已被用于治疗导致视力丧失的局限性脉络膜血管瘤。最近,经瞳孔温热疗法已被应用于脉络膜血管瘤的治疗。本文回顾了36例经瞳孔温热疗法治疗的脉络膜血管瘤病例。其中28例为文献报道病例,10例为作者治疗的病例。经瞳孔温热疗法已被用作脉络膜血管瘤的主要治疗方法(36例)或辅助治疗方法(2例)。经瞳孔温热疗法的目标是使黄斑中心凹的渗出性脱离消退并改善视力。在所有患眼中,黄斑中心凹脱离均消退。在26例治疗前视力≥0.05(20/400)的患眼中,20只眼(77%)视力提高,6只眼(23%)视力保持不变。经瞳孔温热疗法后,16例(42%)肿瘤完全消退,20例(53%)部分消退,2例(5%)在2至44个月的随访中肿瘤厚度无变化。脉络膜血管瘤经瞳孔温热疗法的并发症包括黄斑囊样水肿(3只眼)、视网膜前纤维化(2只眼)、局限性虹膜萎缩(3只眼)和视网膜血管阻塞(1只眼)。尽管许多研究的随访时间有限,但经瞳孔温热疗法尚未发现有任何严重并发症。

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