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经瞳孔温热疗法治疗局限性脉络膜血管瘤:临床特征与治疗结果

Transpupillary thermotherapy for circumscribed choroidal hemangioma: clinical profile and treatment outcome.

作者信息

Sharma Tarun, Krishnan Tandava, Gopal Lingam, Nagpal Amit, Khetan Vikas, Rishi Pukhraj

机构信息

Shri Bhagwan Mahavir Vitreoretinal Services, Tamil Nadu, India.

出版信息

Ophthalmic Surg Lasers Imaging. 2011 Sep-Oct;42(5):360-8. doi: 10.3928/15428877-20110707-01. Epub 2011 Jul 14.

DOI:10.3928/15428877-20110707-01
PMID:21751767
Abstract

BACKGROUND AND OBJECTIVE

To report the outcome of treating circumscribed choroidal hemangioma (CCH) using transpupillary thermotherapy (TTT).

PATIENTS AND METHODS

An infrared diode laser was used at 810 nm with a median spot size of 2.5 mm, power of 550 mW, and duration of 6.5 minutes; the median number of sittings was two. TTT spared the center of the macula when CCH involved the fovea.

RESULTS

The mean age was 36 years (range: 13 to 63 years). CCH was subfoveal in 37.5% of the eyes and exudative retinal detachment was evident in all eyes. The tumor dimensions included thickness (median: 4.05 mm; range: 2.2 to 9.1 mm), horizontal diameter (median: 11 mm; range: 6 to 17.7 mm), and vertical diameter (median: 9.4 mm; range: 5.9 to 15.8 mm). After TTT, visual acuity improved in 44%, was maintained in 37%, and worsened in 19% of eyes. Likewise, tumor regression was achieved in thickness, vertical, and horizontal diameter in proportion of 20%, 15%, and 11%, respectively. The exudative retinal detachment resolved in 94% of eyes at the last follow-up. The median follow-up was 9.5 months.

CONCLUSION

Macula-sparing TTT was effective in causing regression of CCH and resorption of associated exudative retinal detachment, and helped in preserving or improving vision in 81% of treated eyes.

摘要

背景与目的

报告经瞳孔温热疗法(TTT)治疗局限性脉络膜血管瘤(CCH)的结果。

患者与方法

使用波长810nm的红外二极管激光,光斑大小中位数为2.5mm,功率550mW,持续时间6.5分钟;治疗次数中位数为2次。当CCH累及黄斑中心凹时,TTT避开黄斑中心。

结果

平均年龄36岁(范围:13至63岁)。37.5%的患眼CCH位于黄斑中心凹下,所有患眼均有明显的渗出性视网膜脱离。肿瘤大小包括厚度(中位数:4.05mm;范围:2.2至9.1mm)、水平直径(中位数:11mm;范围:6至17.7mm)和垂直直径(中位数:9.4mm;范围:5.9至15.8mm)。TTT治疗后,44%的患眼视力提高,37%的患眼视力维持,19%的患眼视力下降。同样,肿瘤厚度、垂直直径和水平直径的缩小比例分别为20%、15%和11%。在最后一次随访时,94%的患眼渗出性视网膜脱离消退。中位随访时间为9.5个月。

结论

保留黄斑的TTT可有效使CCH缩小并使相关的渗出性视网膜脱离吸收,有助于81%的治疗患眼保留或提高视力。

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