语言任务中功能磁共振成像的时间响应与快速反应时间之间的相关性。
Correlation between temporal response of fMRI and fast reaction time in a language task.
作者信息
Liu Ho-Ling, Liao Wan-Ting, Fang Shin-Yi, Chu Tieh-Chi, Tan Li Hai
机构信息
MRI Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
出版信息
Magn Reson Imaging. 2004 May;22(4):451-5. doi: 10.1016/j.mri.2004.01.003.
Correlation between behavioral parameters and fMRI responses can provide an advanced understanding of the neuronal processes. A lexical decision task was employed to examine the correlation between the reaction time (RT) and the temporal parameters in event-related BOLD responses. Word frequency was manipulated in the experiment. RTs for high-frequency, low-frequency and pseudowords were measured during fMRI (417 +/- 9 ms, 631 +/- 22 ms and 658 +/- 15 ms, respectively). For high-frequency words, RTs were significantly shorter than that for low-frequency and pseudowords (p < 0.0005). In the left inferior frontal region, the FWHM of the fMRI responses was significantly correlated with RT (p < 0.001), which may correspond to areas with sustained activation during the whole processing.
行为参数与功能磁共振成像（fMRI）反应之间的相关性可以提供对神经元过程的深入理解。采用词汇判断任务来检查反应时间（RT）与事件相关血氧水平依赖（BOLD）反应中的时间参数之间的相关性。实验中对词频进行了操控。在功能磁共振成像期间测量了高频、低频和假词的反应时间（分别为417±9毫秒、631±22毫秒和658±15毫秒）。对于高频词，反应时间显著短于低频词和假词（p<0.0005）。在左侧额下回区域，功能磁共振成像反应的半高宽（FWHM）与反应时间显著相关（p<0.001），这可能对应于整个处理过程中持续激活的区域。
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