[人乳头瘤病毒感染的流行病学]

[Epidemiology of HPV infection].

作者信息

Boulanger J-C, Sevestre H, Bauville E, Ghighi C, Harlicot J-P, Gondry J

机构信息

Centre de gynécologie obstétrique, CHU, 124, rue Camille-Desmoulins, 80054 Amiens, France.

出版信息

Gynecol Obstet Fertil. 2004 Mar;32(3):218-23. doi: 10.1016/j.gyobfe.2004.01.013.

DOI:10.1016/j.gyobfe.2004.01.013

PMID:15123119

Abstract

HPV DNA testing using Hybrid Capture 2 (Digene) was added to a program of liquid based (Thinprep, Cytyc) cervical cancer screening in a population of sexually active women aged from 20 to 62 years, without the history of uterine cervix pathology. 14.32% of 3832 women in this population were HPV positive. Positivity peaked in women aged 25-29 (19.4%) and gradually decreased, with 8% of positivity after 60 years. Positivity was independently related to parity, tobacco use and was correlated to cervical pathology. The rate of positivity in this population seems to preclude the use of HPV testing as a primary screening tool.

摘要

在20至62岁无子宫颈病理史的性活跃女性群体中，将使用杂交捕获2代（Digene）进行的人乳头瘤病毒（HPV）DNA检测添加到基于液基（Thinprep，Cytyc）的子宫颈癌筛查项目中。该群体中3832名女性中有14.32%的人HPV呈阳性。阳性率在25至29岁的女性中达到峰值（19.4%），并逐渐下降，60岁以后阳性率为8%。阳性率与产次、吸烟独立相关，且与子宫颈病理相关。该群体中的阳性率似乎排除了将HPV检测用作主要筛查工具的可能性。