局部用前列腺素F（2α）类似物诱发的白发症。
Topical prostaglandin F(2alpha) analog induced poliosis.
作者信息
Chen Celia S, Wells Jane, Craig Jamie E
机构信息
Department of Ophthalmology, Flinders Medical Centre, Bedford Drive, Bedford Park, Adelaide, SA 5042, Australia.
出版信息
Am J Ophthalmol. 2004 May;137(5):965-6. doi: 10.1016/j.ajo.2003.11.020.
PURPOSE
To report poliosis as a side effect associated with topical prostaglandin F(2alpha) (PGF(2alpha)) analogs.
METHOD
Case series.
RESULTS
Seven patients treated with different topical PGF(2alpha) analogs for primary open angle glaucoma developed bilateral poliosis, either alone or in combination with other adverse effects of PGF(2alpha) analog therapy.
CONCLUSION
Poliosis is a possible adverse effect of topical PGF(2alpha) analog therapy which is previously unreported. Topical PGF(2alpha) analog therapy should be included in the differential diagnosis of patients with poliosis.
目的
报告点状白发作为局部用前列腺素F（2α）（PGF（2α））类似物的一种副作用。
方法
病例系列。
结果
7例因原发性开角型青光眼接受不同局部PGF（2α）类似物治疗的患者出现双侧点状白发，可单独出现或与PGF（2α）类似物治疗的其他不良反应同时出现。
结论
点状白发是局部PGF（2α）类似物治疗可能出现的一种此前未报道的不良反应。局部PGF（2α）类似物治疗应纳入点状白发患者的鉴别诊断中。
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