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勃起功能障碍男性中高血压、高脂血症、糖尿病和抑郁症的患病率。

The prevalence of hypertension, hyperlipidemia, diabetes mellitus and depression in men with erectile dysfunction.

作者信息

Seftel Allen D, Sun Peter, Swindle Ralph

机构信息

School of Medicine, Case Western Reserve University and University Hospitals of Cleveland, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, USA.

出版信息

J Urol. 2004 Jun;171(6 Pt 1):2341-5. doi: 10.1097/01.ju.0000125198.32936.38.

Abstract

PURPOSE

We quantified the prevalence of diagnosed hypertension, hyperlipidemia, diabetes mellitus and depression in male health plan members with erectile dysfunction (ED).

MATERIALS AND METHODS

We used a nationally representative managed care claims database that covered 51 health plans with 28 million lives for 1995 through 2002. Based on 272325 identified patients with ED population and age specific prevalence rates were calculated for the same period.

RESULTS

The crude population prevalence rates were 41.6% for hypertension, 42.4% for hyperlipidemia, 20.2% for diabetes mellitus, 11.1% for depression, 23.9% for hypertension and hyperlipidemia, 12.8% for hypertension and diabetes mellitus, and 11.5% for hyperlipidemia and depression. The crude age specific prevalence rates varied across age groups significantly for hypertension (4.5% to 68.4%), hyperlipidemia (3.9% to 52.3%), and diabetes mellitus (2.8% to 28.7%), and significantly less for depression (5.8% to 15.0%). Region adjusted population prevalence rates were 41.2% for hypertension, 41.8% for hyperlipidemia, 19.7% for diabetes mellitus and 11.9% for depression. Only 87163 patients with ED (32%) had no comorbid diagnosis of hypertension, hyperlipidemia, diabetes mellitus or depression.

CONCLUSION

Hypertension, hyperlipidemia, diabetes mellitus and depression were prevalent in patients with ED. This evidence supported the proposition that ED shares common risk factors with these 4 concurrent conditions. Therefore, as a pathophysiological event, ED could be viewed as a potential observable marker for these concurrent diseases. This finding suggests that clinicians could include ED in the assessment profile of these concurrent conditions for earlier detection and treatment.

摘要

目的

我们对患有勃起功能障碍(ED)的男性健康计划成员中已诊断的高血压、高脂血症、糖尿病和抑郁症的患病率进行了量化。

材料与方法

我们使用了一个具有全国代表性的管理式医疗理赔数据库,该数据库涵盖了1995年至2002年期间的51个健康计划,涉及2800万人。基于272325名确诊的ED患者,计算了同期特定年龄的患病率。

结果

高血压的总体患病率为41.6%,高脂血症为42.4%,糖尿病为20.2%,抑郁症为11.1%,高血压和高脂血症为23.9%,高血压和糖尿病为12.8%,高脂血症和抑郁症为11.5%。高血压(4.5%至68.4%)、高脂血症(3.9%至52.3%)和糖尿病(2.8%至28.7%)的特定年龄总体患病率在各年龄组之间差异显著,而抑郁症(5.8%至15.0%)的差异则明显较小。经地区调整后的总体患病率为:高血压41.2%,高脂血症41.8%,糖尿病19.7%,抑郁症11.9%。只有87163名ED患者(32%)没有高血压、高脂血症、糖尿病或抑郁症的合并诊断。

结论

高血压、高脂血症、糖尿病和抑郁症在ED患者中普遍存在。这一证据支持了ED与这四种并发疾病具有共同危险因素的观点。因此,作为一种病理生理事件,ED可被视为这些并发疾病的潜在可观察标志物。这一发现表明,临床医生可将ED纳入这些并发疾病的评估范围,以便早期发现和治疗。

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