Miller Melissa B, Hendren Ryan, Gilligan Peter H
Clinical Microbiology-Immunology Laboratories, University of North Carolina Hospitals, Chapel Hill, North Carolina 27514, USA.
J Clin Microbiol. 2004 May;42(5):2347-9. doi: 10.1128/JCM.42.5.2347-2349.2004.
A North Carolinian developed fatal coccidioidomycosis immediately after bilateral lung transplantation. The donor had previously traveled to Mexico, and the recipient had no travel history to an area where Coccidioides immitis is endemic. Immunosuppressive therapy of the transplant recipient likely reactivated latent Coccidioides infection in the donor lungs, leading to posttransplant coccidioidomycosis.
一名北卡罗来纳州人在接受双侧肺移植后立即患上了致命的球孢子菌病。供体此前曾前往墨西哥,而受体没有前往球孢子菌病流行地区的旅行史。移植受体的免疫抑制治疗可能激活了供体肺部潜伏的球孢子菌感染,导致移植后球孢子菌病。