DiCaudo David J
Department of Dermatology, Mayo Clinic, Scottsdale, AZ, USA.
Semin Cutan Med Surg. 2014 Sep;33(3):140-5. doi: 10.12788/j.sder.0111.
Coccidioidomycosis is a common, environmentally acquired, pulmonary fungal infection in arid and semi-arid regions of the West, especially Arizona and California. The infection is frequently associated with striking cutaneous manifestations. Reactive, immunologically mediated eruptions include erythema nodosum, a generalized exanthem, Sweet syndrome, and reactive granulomatous dermatitis. Less commonly, the skin can harbor the actual organisms as a result of dissemination from the lungs. Dermatologists may play a key role in the recognition of coccidioidomycosis
球孢子菌病是美国西部干旱和半干旱地区常见的、通过环境感染的肺部真菌感染，尤其是亚利桑那州和加利福尼亚州。这种感染常伴有明显的皮肤表现。反应性、免疫介导的皮疹包括结节性红斑、全身性疹、Sweet综合征和反应性肉芽肿性皮炎。较少见的是，皮肤可因肺部播散而含有实际病原体。皮肤科医生在球孢子菌病的识别中可能起关键作用。
