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腹腔镜引导下对子宫纵隔不孕妇女行宫腔镜子宫成形术:生殖结局随访

Hysteroscopic metroplasty under laparoscopic guidance in infertile women with septate uteri: follow-up of reproductive outcome.

作者信息

Litta Pietro, Pozzan Chiara, Merlin Federica, Sacco Giuseppe, Saccardi Carlo, Ambrosini Guido, Capobianco Giampiero, Dessole Salvatore

机构信息

Department of Gynecology and Obstetrics, University of Padua, Padua, Italy.

出版信息

J Reprod Med. 2004 Apr;49(4):274-8.

Abstract

OBJECTIVE

To evaluate the effectiveness of hysteroscopic metroplasty under laparoscopic guidance in the treatment of infertile women with a diagnosis of septate uterus and the impact of this surgical procedure on reproductive outcome.

STUDY DESIGN

From January 1996 to December 2000, 36 women referred to our endoscopy center underwent hysteroscopic metroplasty. Follow-up covered the incidence of pregnancy, term pregnancies and mode of delivery.

RESULTS

The mean age of the patients was 31.9 +/- 3.9 years (range, 23-39). One patient (3%) dropped out during follow-up. There were no intraoperative or postoperative complications. The mean interval from metroplasty to conception was 11.3 +/- 9.2 months (range, 2.0-35.5). Twenty of 35 (57%) women had a history of > or = 1 spontaneous abortions, and 18 of the 20 (90%) achieved pregnancy, with 15 of 18 (83%) term deliveries (10 vaginal deliveries and 5 cesarean sections). Fifteen of 35 patients (43%) were nulliparous, and 8 of 15 (53.3%) had term deliveries (1 cesarean section).

CONCLUSION

Hysteroscopic metroplasty under laparoscopic guidance is safe, allows spontaneous delivery and short-term pregnancy planning, is particularly successful in infertile women with a history of > or = 1 spontaneous abortions.

摘要

目的

评估腹腔镜引导下宫腔镜子宫成形术治疗诊断为纵隔子宫的不孕妇女的有效性,以及该手术对生殖结局的影响。

研究设计

1996年1月至2000年12月,36名转诊至我们内镜中心的妇女接受了宫腔镜子宫成形术。随访内容包括妊娠发生率、足月妊娠率和分娩方式。

结果

患者的平均年龄为31.9±3.9岁(范围23 - 39岁)。1名患者(3%)在随访期间退出。无术中或术后并发症。子宫成形术至受孕的平均间隔时间为11.3±9.2个月(范围2.0 - 35.5个月)。35名妇女中有20名(57%)有≥1次自然流产史,其中20名中的18名(90%)成功受孕,18名中的15名(83%)足月分娩(10例阴道分娩和5例剖宫产)。35名患者中有15名(43%)未生育,15名中的8名(53.3%)足月分娩(1例剖宫产)。

结论

腹腔镜引导下宫腔镜子宫成形术安全,可实现自然分娩和短期妊娠计划,对于有≥1次自然流产史的不孕妇女尤其成功。

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