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利莫那班 赛诺菲-圣德拉堡集团。

Rimonabant Sanofi-Synthélabo.

作者信息

Fernandez Jose R, Allison David B

机构信息

University of Alabama at Birmingham, Department of Nutrition Sciences, Ryals Public Health Building, 1665 University Blvd, Birmingham, AL 35294-0022, USA.

出版信息

Curr Opin Investig Drugs. 2004 Apr;5(4):430-5.

Abstract

Rimonabant, an antagonist of central cannabinoid type 1 (CB1) receptors, is being developed by Sanofi-Synthélabo for the potential treatment of obesity and as a potential smoking cessation agent. Phase III trials were initiated for obesity in August 2001 and were ongoing in September 2003. By September 2002, the compound had entered phase III trials for smoking cessation, and these trials were ongoing in September 2003.

摘要

利莫那班是一种中枢1型大麻素(CB1)受体拮抗剂,赛诺菲-圣德拉堡公司正在对其进行研发,用于潜在治疗肥胖症以及作为一种潜在的戒烟药物。2001年8月启动了针对肥胖症的III期试验,2003年9月试验仍在进行。到2002年9月,该化合物已进入戒烟的III期试验,2003年9月这些试验仍在进行。

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