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前列腺近距离放射治疗的患者选择:更多是神话而非事实。

Patient selection for prostate brachytherapy: more myth than fact.

作者信息

Merrick Gregory S, Wallner Kent E, Butler Wayne M

机构信息

Schiffler Cancer Center, Wheeling Hospital, Wheeling Jesuit University, Wheeling, West Virginia 26003-6300, USA.

出版信息

Oncology (Williston Park). 2004 Apr;18(4):445-52; discussion 452, 455-7.

PMID:15134353
Abstract

Prostate brachytherapy efficacy and morbidity are primarily dependent on implant quality and patient management. While most alleged contraindications to brachytherapy have been propagated based on physician bias rather than clinical data, a number of evidence-based factors contributing to radiation-related morbidity have accumulated. Refinements in patient selection may result in further improvements in biochemical and quality-of-life outcomes. Herein, we have summarized evidence-based vs unsubstantiated patient selection factors that affect outcome.

摘要

前列腺近距离放射治疗的疗效和发病率主要取决于植入质量和患者管理。虽然大多数所谓的近距离放射治疗禁忌症是基于医生的偏见而非临床数据传播开来的,但一些导致放射性发病率的循证因素已经积累起来。患者选择的优化可能会进一步改善生化指标和生活质量。在此,我们总结了影响治疗结果的循证与无充分依据的患者选择因素。

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引用本文的文献

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Int Braz J Urol. 2019 Mar-Apr;45(2):288-298. doi: 10.1590/S1677-5538.IBJU.2018.0142.
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Dosimetric coverage of the prostate, normal tissue sparing, and acute toxicity with high-dose-rate brachytherapy for large prostate volumes.大体积前列腺高剂量率近距离放射治疗的前列腺剂量覆盖、正常组织保护及急性毒性
Int Braz J Urol. 2015 May-Jun;41(3):435-41. doi: 10.1590/S1677-5538.IBJU.2014.0289.
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The efficacy of conventional external beam, three-dimensional conformal, intensity-modulated, particle beam radiation, and brachytherapy for localized prostate cancer.
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Curr Urol Rep. 2005 May;6(3):194-209. doi: 10.1007/s11934-005-0008-3.