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与被动病例发现相比,通过主动病例发现诊断的肺结核患者的疾病范围。

Extent of pulmonary tuberculosis in patients diagnosed by active compared to passive case finding.

作者信息

Ward H A, Marciniuk D D, Pahwa P, Hoeppner V H

机构信息

Department of Medicine, Division of Tuberculosis Control, Royal University Hospital, University of Saskatchewan, Saskatoon, Canada.

出版信息

Int J Tuberc Lung Dis. 2004 May;8(5):593-7.

Abstract

OBJECTIVE

To compare the extent of pulmonary tuberculosis amongst patients detected by screening (active case finding) with that in patients detected by symptoms (passive case finding), and to identify early symptoms of pulmonary tuberculosis.

SUBJECTS AND METHOD

In this cross-sectional study, Tuberculosis Control Program records were reviewed for method of detection and extent of disease in Canadian Plains Aborigines between 1 January 1991 and 30 June 1999.

RESULTS

Among 903 cases, method of detection was active in 450 (49.8%) and passive in 453 (50.2%). Cough and fever were the most common symptoms in both methods of detection, and were significantly more frequent in passive detection (P < 0.05). Cough was present in 59% and fever in 19% of actively detected cases compared to 84% and 47%, respectively, of passively detected cases. Age was significantly different between the two methods of detection. Hemoptysis, weight loss and method of detection were associated with increased risk of infectiousness among those < or = 19 years, while cough, hemoptysis and weight loss were associated among those >19 years.

CONCLUSION

Method of detection rather than age contributed to infectiousness in children and adolescents. Daily cough for more than 1 month and unexplained fever for more than 1 week should raise the suspicion for TB.

摘要

目的

比较通过筛查(主动病例发现)检测出的肺结核患者与通过症状(被动病例发现)检测出的肺结核患者中肺结核的患病程度,并确定肺结核的早期症状。

对象与方法

在这项横断面研究中,回顾了1991年1月1日至1999年6月30日期间加拿大平原原住民结核病控制项目记录,以了解检测方法和疾病程度。

结果

在903例病例中,450例(49.8%)通过主动检测发现,453例(50.2%)通过被动检测发现。咳嗽和发热是两种检测方法中最常见的症状,且在被动检测中更为常见(P<0.05)。主动检测出的病例中59%有咳嗽症状,19%有发热症状,而被动检测出的病例中这两个比例分别为84%和47%。两种检测方法的患者年龄存在显著差异。在19岁及以下人群中,咯血、体重减轻和检测方法与传染性增加有关,而在19岁以上人群中,咳嗽、咯血和体重减轻与传染性有关。

结论

在儿童和青少年中,导致传染性的因素是检测方法而非年龄。持续咳嗽超过1个月以及不明原因发热超过1周应引起对结核病的怀疑。

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