Triantafyllidi Helen, Vavouranakis Manolis, Arvaniti Chrisa, Stefanadis Christodoulos, Toutouzas Pavlos
Department of Cardiology, Medical School, University of Athens, Hippokration Hospital, Athens, Greece.
Acta Cardiol. 2004 Apr;59(2):153-8. doi: 10.2143/AC.59.2.2005170.
Using intracoronary ultrasound we studied the anatomical characteristics and the pulsatile changes of the coronary arterial wall of ectatic coronary arteries in patients with atherosclerotic coronary artery disease who underwent percutaneous transluminal coronary angioplasty.
Three study groups were formed according to the characteristics of the coronary segments, (a) group CES, coronary segments with ectasia, n = 10, (b) group NES, normal coronary segments adjacent to ectatic sites, n = 10 and (c) group NAS, normal coronary segments adjacent to atherosclerotic sites, n = 30. Pulsatile changes was defined as CSLA(syst)-CSLA(dia)/CSLA(dia) x 100. Coronary segments with ectasia (CES group) had significantly thinner media than the NAS group. Furthermore, increased vessel wall pulsatile changes were found in the ectatic segments.
Atherosclerotic ectatic coronary segments reveal diminished media thickness and increased coronary arterial wall pulsatile changes, which may be indicative of a mechanically and structurally weak artery prone to aneurysm formation.
我们使用冠状动脉内超声研究了接受经皮冠状动脉腔内血管成形术的动脉粥样硬化性冠状动脉疾病患者扩张冠状动脉的解剖特征和冠状动脉壁的搏动变化。
根据冠状动脉节段的特征形成三个研究组，（a）CES组，有扩张的冠状动脉节段，n = 10；（b）NES组，与扩张部位相邻的正常冠状动脉节段，n = 10；（c）NAS组，与动脉粥样硬化部位相邻的正常冠状动脉节段，n = 30。搏动变化定义为CSLA（收缩期）-CSLA（舒张期）/CSLA（舒张期）×100。有扩张的冠状动脉节段（CES组）的中膜明显比NAS组薄。此外，在扩张节段发现血管壁搏动变化增加。
动脉粥样硬化性扩张冠状动脉节段显示中膜厚度减小和冠状动脉壁搏动变化增加，这可能表明动脉在机械和结构上较弱，易于形成动脉瘤。
