[豚鼠皮层神经元胆碱能反应的温度敏感性]

[Temperature sensitivity of the cholinergic response in cortical neurons of guinea pigs].

作者信息

Mednikova Iu S, Pasikova N V

机构信息

Institute of Higher Nervous Activity and Neurophysiology, Russian Acad. Sci., Moscow 117485, Russia.

出版信息

Ross Fiziol Zh Im I M Sechenova. 2004 Feb;90(2):193-201.

PMID:15143507

Abstract

A temperature change from 20 to 36 degrees C results in a significant increase of neuronal responses to iontophoretic application of acetylcholine in parietal cortex slices. The most intensive changes in cholinergic responses occurred in two temperature zones: 27-29 degrees C and 34-36 degrees C. Increase in the responses to acetylcholine accompany with increasing spontaneous spike activity.

摘要

温度从20摄氏度变化到36摄氏度会导致顶叶皮层切片中神经元对离子电渗法施加乙酰胆碱的反应显著增加。胆碱能反应最强烈的变化发生在两个温度区域：27 - 29摄氏度和34 - 36摄氏度。对乙酰胆碱反应的增加伴随着自发棘波活动的增加。