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豚鼠脑皮质神经元胆碱能反应的温度敏感性

The temperature sensitivity of the cholinergic responses of cortical neurons in the guinea pig brain.

作者信息

Mednikova Yu S, Pasikova N V

机构信息

Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, 5a Butlerov Street, 117485 Moscow, Russia.

出版信息

Neurosci Behav Physiol. 2005 Jul;35(6):615-21. doi: 10.1007/s11055-005-0101-6.

Abstract

Studies on slices of the parietal cortex of the guinea-pig brain showed that a change in temperature from 20 degrees C to 36 degrees C led to increases in responses to microintophoretic application of acetylcholine to individual nerve cells. The greatest changes occurred over two temperature ranges: 27-29 degrees C and 34-36 degrees C. Increases in the cholinergic response were accompanied by increases in the spontaneous activity of the neurons.

摘要

对豚鼠大脑顶叶皮质切片的研究表明,温度从20摄氏度变化到36摄氏度会导致单个神经细胞对微量电泳施加乙酰胆碱的反应增强。最大的变化发生在两个温度范围内:27 - 29摄氏度和34 - 36摄氏度。胆碱能反应的增强伴随着神经元自发活动的增加。

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