Chen Ruoling, Hu Zhi, Qin Xia, Xu Xiaochao, Copeland John R M
School of Health Administration, Anhui Medical University, Hefei, China.
Int J Geriatr Psychiatry. 2004 May;19(5):407-13. doi: 10.1002/gps.1103.
Previously published studies of prevalence of depression in older people in China showed much variation in the results, while the pooled prevalence is low. In this study we used a standardised method, the Geriatric Mental State (GMS) to investigate the prevalence of depression in older people in China, validate the GMS-AGECAT depression cases and examine the relationship between depression and socio-economic deprivation.
1736 subjects aged > or =65 were recruited from Hefei city, China. They were interviewed at home by a survey team from Anhui Medical Universtiy using the GMS and other interviews. Their mental disorders were diagnosed by the Automated Geriatric Examination for Computer Assisted Taxonomy (AGECAT). Chinese psychiatrists re-examined depression cases and their controls.
39 depressed cases were diagnosed by the GMS-AGECAT. Age-standardised prevalence was 2.2% (95% CI 1.5-2.9), which was about five-times lower than that of older people in Liverpool, UK. Agreement on depression diagnoses between the GMS-AGECAT and local Chinese psychiatrists was 83.6%, with a Kappa of 0.67 (p<0.001). Depression was significantly related to socio-economic deprivation.
This community-based study suggested a low prevalence of depression in older people in urban China. Approved training in the use of the GMS-AGECAT in mainland China should make it possible to carry out a large scale epidemiological study on depression in the Chinese elderly population to investigate its geographic variation and risk factors. The dose-response relation between socio-economic deprivation and depression indicates that strategies for tackling inequality in depression in elderly are urgently needed in China.
此前发表的关于中国老年人抑郁症患病率的研究结果差异很大,而汇总患病率较低。在本研究中,我们使用标准化方法——老年精神状态检查(GMS)来调查中国老年人抑郁症的患病率,验证GMS-AGECAT抑郁症病例,并研究抑郁症与社会经济剥夺之间的关系。
从中国合肥市招募了1736名年龄≥65岁的受试者。安徽医科大学的一个调查团队在他们家中使用GMS和其他访谈工具对他们进行了访谈。他们的精神障碍由计算机辅助分类的老年自动检查(AGECAT)进行诊断。中国精神科医生对抑郁症病例及其对照进行了重新检查。
GMS-AGECAT诊断出39例抑郁症病例。年龄标准化患病率为2.2%(95%可信区间1.5-2.9),约为英国利物浦老年人患病率的五分之一。GMS-AGECAT与中国当地精神科医生在抑郁症诊断上的一致性为83.6%,kappa值为0.67(p<0.001)。抑郁症与社会经济剥夺显著相关。
这项基于社区的研究表明中国城市老年人抑郁症患病率较低。在中国内地批准开展使用GMS-AGECAT的培训,将有可能对中国老年人群体进行大规模抑郁症流行病学研究,以调查其地理差异和风险因素。社会经济剥夺与抑郁症之间的剂量反应关系表明,中国迫切需要制定应对老年人抑郁症不平等问题的策略。