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中国合肥老年人抑郁症的社区研究——GMS-AGECAT患病率、病例验证及社会经济相关因素

A community-based study of depression in older people in Hefei, China--the GMS-AGECAT prevalence, case validation and socio-economic correlates.

作者信息

Chen Ruoling, Hu Zhi, Qin Xia, Xu Xiaochao, Copeland John R M

机构信息

School of Health Administration, Anhui Medical University, Hefei, China.

出版信息

Int J Geriatr Psychiatry. 2004 May;19(5):407-13. doi: 10.1002/gps.1103.

Abstract

OBJECTIVE

Previously published studies of prevalence of depression in older people in China showed much variation in the results, while the pooled prevalence is low. In this study we used a standardised method, the Geriatric Mental State (GMS) to investigate the prevalence of depression in older people in China, validate the GMS-AGECAT depression cases and examine the relationship between depression and socio-economic deprivation.

METHODS

1736 subjects aged > or =65 were recruited from Hefei city, China. They were interviewed at home by a survey team from Anhui Medical Universtiy using the GMS and other interviews. Their mental disorders were diagnosed by the Automated Geriatric Examination for Computer Assisted Taxonomy (AGECAT). Chinese psychiatrists re-examined depression cases and their controls.

RESULTS

39 depressed cases were diagnosed by the GMS-AGECAT. Age-standardised prevalence was 2.2% (95% CI 1.5-2.9), which was about five-times lower than that of older people in Liverpool, UK. Agreement on depression diagnoses between the GMS-AGECAT and local Chinese psychiatrists was 83.6%, with a Kappa of 0.67 (p<0.001). Depression was significantly related to socio-economic deprivation.

CONCLUSIONS

This community-based study suggested a low prevalence of depression in older people in urban China. Approved training in the use of the GMS-AGECAT in mainland China should make it possible to carry out a large scale epidemiological study on depression in the Chinese elderly population to investigate its geographic variation and risk factors. The dose-response relation between socio-economic deprivation and depression indicates that strategies for tackling inequality in depression in elderly are urgently needed in China.

摘要

目的

此前发表的关于中国老年人抑郁症患病率的研究结果差异很大,而汇总患病率较低。在本研究中,我们使用标准化方法——老年精神状态检查(GMS)来调查中国老年人抑郁症的患病率,验证GMS-AGECAT抑郁症病例,并研究抑郁症与社会经济剥夺之间的关系。

方法

从中国合肥市招募了1736名年龄≥65岁的受试者。安徽医科大学的一个调查团队在他们家中使用GMS和其他访谈工具对他们进行了访谈。他们的精神障碍由计算机辅助分类的老年自动检查(AGECAT)进行诊断。中国精神科医生对抑郁症病例及其对照进行了重新检查。

结果

GMS-AGECAT诊断出39例抑郁症病例。年龄标准化患病率为2.2%(95%可信区间1.5-2.9),约为英国利物浦老年人患病率的五分之一。GMS-AGECAT与中国当地精神科医生在抑郁症诊断上的一致性为83.6%,kappa值为0.67(p<0.001)。抑郁症与社会经济剥夺显著相关。

结论

这项基于社区的研究表明中国城市老年人抑郁症患病率较低。在中国内地批准开展使用GMS-AGECAT的培训,将有可能对中国老年人群体进行大规模抑郁症流行病学研究,以调查其地理差异和风险因素。社会经济剥夺与抑郁症之间的剂量反应关系表明,中国迫切需要制定应对老年人抑郁症不平等问题的策略。

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