Guerra M, Prina A M, Ferri C P, Acosta D, Gallardo S, Huang Y, Jacob K S, Jimenez-Velazquez I Z, Llibre Rodriguez J J, Liu Z, Salas A, Sosa A L, Williams J D, Uwakwe R, Prince M
Institute of Memory, Depression and Disease Risk, Avda Constructores 1230, Lima 12, Peru; Centre for Global Mental Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King׳s College London, London, UK; Peruvian University, Cayetano, Heredia, Lima, Peru.
Centre for Global Mental Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King׳s College London, London, UK.
J Affect Disord. 2016 Jan 15;190:362-368. doi: 10.1016/j.jad.2015.09.004. Epub 2015 Oct 23.
Current estimates of the prevalence of depression in later life mostly arise from studies carried out in Europe, North America and Asia. In this study we aimed to measure the prevalence of depression using a standardised method in a number of low and middle income countries (LMIC).
A one-phase cross-sectional survey involving over 17,000 participants aged 65 years and over living in urban and rural catchment areas in 13 sites from 9 countries (Cuba, Dominican Republic, Puerto Rico, Mexico, Venezuela, Peru, China, India and Nigeria). Depression was assessed and compared using ICD-10 and EURO-D criteria.
Depression prevalence varied across sites according to diagnostic criteria. The lowest prevalence was observed for ICD-10 depressive episode (0.3 to 13.8%). When using the EURO-D depression scale, the prevalence was higher and ranged from 1.0% to 38.6%. The crude prevalence was particularly high in the Dominican Republic and in rural India. ICD-10 depression was also associated with increased age and being female.
Generalisability of findings outside of catchment areas is difficult to assess.
Late life depression is burdensome, and common in LMIC. However its prevalence varies from culture to culture; its diagnosis poses a significant challenge and requires proper recognition of its expression.
目前对晚年抑郁症患病率的估计大多来自欧洲、北美和亚洲开展的研究。在本研究中，我们旨在采用标准化方法测量一些低收入和中等收入国家（LMIC）的抑郁症患病率。
一项单阶段横断面调查，涉及来自9个国家（古巴、多米尼加共和国、波多黎各、墨西哥、委内瑞拉、秘鲁、中国、印度和尼日利亚）13个地点城乡集水区的17000多名65岁及以上的参与者。使用国际疾病分类第10版（ICD - 10）和欧洲抑郁症量表（EURO - D）标准对抑郁症进行评估和比较。
根据诊断标准，各地点的抑郁症患病率有所不同。ICD - 10抑郁发作的患病率最低（0.3%至13.8%）。使用EURO - D抑郁量表时，患病率较高，范围为1.0%至38.6%。粗患病率在多米尼加共和国和印度农村地区特别高。ICD - 10抑郁症也与年龄增长和女性相关。
很难评估集水区以外地区研究结果的普遍性。
晚年抑郁症负担沉重，在低收入和中等收入国家很常见。然而，其患病率因文化而异；其诊断构成重大挑战，需要正确认识其表现形式。
