Joshi H C, Palevitz B A
Dept of Anatomy and Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Trends Cell Biol. 1996 Feb;6(2):41-4. doi: 10.1016/0962-8924(96)81008-7.
In animal cells, microtubule assembly is usually initiated at one specialized structure, the centrosome. By contrast, in plant cells, microtubule assembly begins at a variety of locations within the cell. A member of the tubulin gene family, gamma-tubulin, is localized to the centrosome in animal cells and is important in the assembly of microtubules in vivo. Recent reports have identified gamma-tubulin genes in plants and have described the complex intracellular distribution of the encoded polypeptides. Here, Harish Joshi and Barry Palevitz comment upon how this information may help elucidate the organizing principles of the complex arrays of microtubules in plant cells.
在动物细胞中,微管组装通常起始于一个特殊结构——中心体。相比之下,在植物细胞中,微管组装始于细胞内的多个位置。微管蛋白基因家族的成员γ-微管蛋白定位于动物细胞的中心体,并且在体内微管组装过程中起重要作用。最近的报道已在植物中鉴定出γ-微管蛋白基因,并描述了所编码多肽在细胞内的复杂分布。在此,哈里什·乔希和巴里·帕莱维茨评论了这些信息如何有助于阐明植物细胞中微管复杂阵列的组织原理。