肌梭传入纤维中枢和外周末梢中的囊泡谷氨酸转运体免疫反应性

Vesicular glutamate transporter immunoreactivity in the central and peripheral endings of muscle-spindle afferents.

作者信息

Wu Sheng-Xi, Koshimizu Yoshinori, Feng Yu-Peng, Okamoto Keiko, Fujiyama Fumino, Hioki Hiroyuki, Li Yun-Qing, Kaneko Takeshi, Mizuno Noboru

机构信息

Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.

出版信息

Brain Res. 2004 Jun 18;1011(2):247-51. doi: 10.1016/j.brainres.2004.03.047.

DOI:10.1016/j.brainres.2004.03.047

PMID:15157812

Abstract

Expression of vesicular glutamate transporters (VGLUTs: VGLUT1, VGLUT2 and VGLUT3) in muscle spindle afferents was examined in rats. VGLUT1 immunoreactivity was detected in the sensory endings on the equatorial and juxta-equatarial regions of intrafusal fibers as well as in many axon terminals within lamina IX of the spinal cord. VGLUT1 might be expressed not only in the central axon terminals but also in the peripheral sensory endings of muscle-spindle afferents.

摘要

在大鼠中检测了囊泡谷氨酸转运体（VGLUTs：VGLUT1、VGLUT2和VGLUT3）在肌梭传入纤维中的表达。在梭内纤维赤道和近赤道区域的感觉末梢以及脊髓IX层内的许多轴突终末中检测到VGLUT1免疫反应性。VGLUT1可能不仅在中枢轴突终末表达，也在肌梭传入纤维的外周感觉末梢表达。