Reaven Gerald
Division of Cardiovascular Medicine, Stanford University School of Medicine, FALK CVRC, 300 Pasteur Drive, Stanford, CA 94305, USA.
Endocrinol Metab Clin North Am. 2004 Jun;33(2):283-303. doi: 10.1016/j.ecl.2004.03.002.
The goal of this article is to differentiate the insulin resistance syndrome from the metabolic syndrome. In the case of the insulin resistance syndrome, the abnormalities and clinical syndromes that are increased in prevalence in insulin-resistant individuals have been summarized, with a brief discussion of the causal relationship between insulin resistance, compensatory hyperinsulinemia, and associated consequences. Discussion of the metabolic syndrome has focused on the five criteria chosen by the adult treatment panel III to diagnose the syndrome, evaluating them in terms of their relationship to insulin resistance and their role as cardiovascular disease risk factors.
本文的目的是区分胰岛素抵抗综合征与代谢综合征。对于胰岛素抵抗综合征,总结了胰岛素抵抗个体中患病率增加的异常情况和临床综合征,并简要讨论了胰岛素抵抗、代偿性高胰岛素血症及相关后果之间的因果关系。对代谢综合征的讨论集中在成人治疗小组III选择的用于诊断该综合征的五条标准上,从它们与胰岛素抵抗的关系及其作为心血管疾病危险因素的作用方面进行评估。