Wilkinson S M, English J S, Smith N P, Wilson-Jones E, Winkelmann R K
Department of Dermatology, North Staffordshire Hospital Centre, Stoke-on-Trent, U.K.
Clin Exp Dermatol. 1992 Mar;17(2):87-93. doi: 10.1111/j.1365-2230.1992.tb00171.x.
Erythema elevatum diutinum is a syndrome of vasculitis in which lesions, typically over the extensor surfaces, showed a mixed inflammatory infiltrate on biopsy. We describe a series of 13 patients. The most common association in our series was with hypergammaglobulinemia; both mono and polyclonal. Chronic infection, not streptococcal, was a less frequent finding although two of three patients had a positive reaction to the intradermal injection of streptococcal antigen. Dapsone remains the initial treatment of choice.
持久性隆起性红斑是一种血管炎综合征，其皮损通常位于伸侧表面，活检显示有混合性炎性浸润。我们描述了一组13例患者。在我们的病例系列中，最常见的关联是与高球蛋白血症相关，包括单克隆和多克隆。慢性感染（非链球菌感染）是较少见的发现，尽管3例患者中有2例对链球菌抗原皮内注射呈阳性反应。氨苯砜仍然是首选的初始治疗药物。
