Wollina Uwe, Krönert Claudia, Koch André, Schönlebe Jacqueline, Vojvodic Aleksandra, Lotti Torello
Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany.
Institute of Pathology "Georg Schmorl", Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany.
Open Access Maced J Med Sci. 2019 Aug 30;7(18):3039-3042. doi: 10.3889/oamjms.2019.765. eCollection 2019 Sep 30.
Erythema elevatum diutinum (EED) belongs to the spectrum of cutaneous leukocytoclastic vasculitides. EED is a very rare dermatosis presenting with reddish to browning papules and plaques. EED may be associated with infections, hematologic and autoimmune disorders.
We present two patients with EED, a 50-year-old woman and a 42-year-old man. While the woman shows an association with colitis ulcerosa, the man had an anti-thrombin deficiency. Treatment was started with oral corticosteroid and dapsone, respectively. In both cases, there was a partial and temporary response.
EED is a rare vasculitis with an unusual clinical presentation and a chronic course. Response to treatment is unsatisfactory and in the long-term run sometimes frustrating.
持久性隆起性红斑（EED）属于皮肤白细胞破碎性血管炎范畴。EED是一种非常罕见的皮肤病，表现为红色至褐色丘疹和斑块。EED可能与感染、血液系统及自身免疫性疾病有关。
我们报告了两名EED患者，一名50岁女性和一名42岁男性。该女性患者与溃疡性结肠炎有关，而男性患者存在抗凝血酶缺乏。分别开始使用口服糖皮质激素和氨苯砜进行治疗。在这两个病例中，均有部分且短暂的反应。
EED是一种罕见的血管炎，临床表现不寻常且病程呈慢性。对治疗的反应不尽人意，从长远来看有时令人沮丧。
Zotero 插件
